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Table 2 Putative identity of the significantly differentially expressed lipids between AD patients with and without severe OSA

From: Blood-based lipidomic signature of severe obstructive sleep apnoea in Alzheimer’s disease

Putative identity

Class

Mass

RT (min)

Mass/z

Fold change

p

LysoPC(18:0)

PL

523.3624

3.63

524.3624

1.628

0.001

PC(40:6)

PL

893.6143

7.40

892.6143

1.307

0.002

DG(40:3)

GL

734.5885

9.16

733.5885

1.365

0.002

OxTG(62:12)

GL

1059.885

9.98

1060.885

1.669

0.003

PE(P-40:6)

PL

775.5565

7.63

776.5565

1.408

0.006

OxPC(42:9)

PL

903.5824

6.56

904.5824

1.467

0.007

Cer(O-37:4)/OxCer(37:5)

SP

587.4894

7.78

588.4894

0.753

0.012

PE(P-36:4)

PL

723.5188

7.25

724.5188

1.259

0.013

OxTG(58:5)

GL

1017.834

9.82

1018.834

1.358

0.019

LysoPC(16:0)

PL

555.3516

2.74

554.3516

1.333

0.021

Cis-8,11,14,17-Eicosatetraenoic acid

FA

364.2588

3.83

363.2588

1.402

0.024

PC(37:6)

PL

791.5414

6.55

792.5414

0.671

0.024

TG(O-56:9)

GL

924.7008

7.11

925.7008

1.339

0.024

PG(33:0)

PL

737.5363

7.51

736.5363

1.418

0.025

PC(35:4)

PL

749.5353

7.33

748.5353

1.32

0.027

TG(O-56:1)

GL

902.8486

7.30

903.8486

0.74

0.028

LysoPC(18:1)

PL

521.3469

2.89

522.3469

1.287

0.03

PS(42:2)

PL

853.6181

7.39

852.6181

0.714

0.032

OxTG(58:6)

GL

1015.822

9.66

1016.822

1.566

0.032

PE(P-36:1)

PL

729.5663

8.11

728.5663

1.48

0.034

LysoPA(18:4)

PL

430.2058

3.62

429.2058

1.481

0.036

OxAcCar(18:0)

FA

443.3681

4.07

444.3681

0.715

0.037

TG(58:8)

GL

990.7796

10.02

989.7796

1.454

0.04

9,10-Epoxyoctadecenoic acid

FA

278.2241

2.62

277.2241

1.705

0.04

CL(78:2)

PL

1605.186

7.56

1604.186

1.334

0.043

  1. Definition of abbreviations: GL glycerolipid, PL phospholipid, FA fatty acid, SP sphingolipid, LysoPC lysophosphatidylcholine, PC phosphatylcholine, OxPC oxidized phosphatidylcholine, DG diglyceride, TG triglyceride, OxTG oxidized triglyceride, PE(P) phosphatidylethanolamine plasmalogen, Cer ceramide, OxCer oxidized ceramide, PG phosphatidylglycerol, PS phosphatidylserine, LysoPA lysophosphatidic acid, OxAcCar oxidized acylcarnitine, CL Cardiolipin