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Table 5 Summary of baseline characteristics and plasma biomarker levels of the Alzheimer disease group according to LB α-syn status

From: Diagnostic value of plasma p-tau181, NfL, and GFAP in a clinical setting cohort of prevalent neurodegenerative dementias

 

α-syn+ (n = 15)

α-syn− (n = 82)

p value

Age, years

67.7 (8.5)

67.9 (9.5)

0.939

Sex (female)

6 (40.0%)

48 (58.5%)

0.259

MMSE, /30

22.1 (6.9)

21.9 (6.1)

0.695

Plasma NfL (pg/mL)

20.1 (15.5–27.7)

22.0 (17.1–27.9)

0.550

Plasma p-tau181 (pg/mL)

3.0 (2.4–5.0)

3.3 (2.4–4.2)

0.807

Plasma GFAP (pg/mL)

338.9 (245.1–475.8)

413.6 (306.1–509.7)

0.228

  1. Age and MMSE are expressed as mean (SD), while biomarker data are presented as median (IQR range)
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Alzheimer's Research & Therapy

ISSN: 1758-9193