Table 1 Demographic information of the study datasets
From: Distinct sex-specific DNA methylation differences in Alzheimer’s disease
Dataset | female samples | male samples | ||||
|---|---|---|---|---|---|---|
sample | subjects1 | age | sample | subjects1 | age2 | |
(N) | (N) | mean (SD) | (N) | (N) | mean (SD) | |
sex-specific meta-analysis | ||||||
ADNI | ||||||
cases | 111 | 69 | 77.81 (6.57) | 180 | 119 | 79.08 (6.53) |
controls | 253 | 110 | 76.93 (6.77) | 249 | 100 | 79.12 (6.21) |
Total | 364 | 179 | 77.27 (6.69) | 429 | 219 | 79.1 (6.37) |
AIBL | ||||||
cases | 77 | 77 | 77.1 (6.06) | 59 | 59 | 76.1 (5.53) |
controls | 191 | 191 | 71.9 (5.07) | 164 | 164 | 72.2 (4.91) |
Total | 268 | 268 | 73.4 (5.87) | 223 | 223 | 73.3 (5.36) |
validation of methylation risk scores | ||||||
AddNeuroMed | ||||||
cases | 53 | 53 | 76.38 (5.98) | 30 | 30 | 77.5 (5.3) |
controls | 54 | 54 | 73.26 (5.44) | 34 | 34 | 74.53 (5.21) |
Total | 107 | 107 | 74.8 (5.9) | 64 | 64 | 75.92 (5.42) |