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Table 1 Demographic characteristics and episodic memory scores

From: Neural correlates of episodic memory in adults with Down syndrome and Alzheimer’s disease

 

All participants

Asymptomatic

Symptomatic

p-values

(N = 139)

(N = 85)

(N = 54)

Age (mean, sd)

43.6 (10.9)

38.5 (10.1)

52.2 (4.6)

<0.001

Female sex, n (%)

64 (46)

37 (43.5)

27 (50)

0.456

Severity of ID, n (%)

   

0.288

 Mild

46 (33.1)

31 (36.5)

15 (27.8)

 

 Moderate

93 (66.9)

54 (63.5)

39 (72.2)

 

Time between MRI and mCRT, days (mean, sd)

108.2 (81.4)

116.2 (79.0)

95.5 (84.2)

0.088

mCRT scores (mean, sd)

 Trial 1 free recall (0–12)

4.3 (2.3)

5.4 (1.9)

2.5 (1.7)

<0.001

 Trial 3 free recall (0–12)

5.8 (2.9)

7.7 (1.7)

2.7 (2.6)

<0.001

 Free immediate recall score (0–36)

15.3 (7.4)

19.8 (4.7)

7.7 (5.3)

<0.001

 Total immediate score (0–36)

29.5 (9.3)

35 (1.6)

20.7 (9.9)

<0.001

 Free delayed recall score (0–12)

5 (3.5)

6.8 (2.7)

1.7 (2.4)

<0.001

 Total delayed score (0–12)

9.7 (3.3)

11.5 (1.0)

6.3 (3.6)

<0.001

  1. p values are given for comparison between asymptomatic and symptomatic subjects. Age refers to the age recorded on the day of the mCRT administration. Brackets next to each episodic memory measure reflect the total possible range of scores
  2. ID Intellectual disability, mCRT Modified Cued Recall Test