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Table 3 Influence of regional amyloid deposition on conversion to dementia

From: The impact of subthreshold levels of amyloid deposition on conversion to dementia in patients with amyloid-negative amnestic mild cognitive impairment

  Cutoff SUVR AUC Sensitivity (%) Specificity (%) P value DeLong’s test P value
L) Temporal cortex 0.94203 0.678 (0.571–0.786) 82.1 50.0 < 0.001  
R) Temporal cortex 0.94333 0.624 (0.51–0.737) 74.4 53.1 < 0.001  
L) Parietal cortex 1.00438 0.762 (0.665–0.859) 84.6 68.8 < 0.001  
R) Parietal cortex 1.00589 0.724 (0.623–0.825) 79.5 67.2 < 0.001  
L) Precuneus 1.02879 0.721 (0.617–0.824) 79.5 60.9 < 0.001  
L) Occipital cortex 1.07716 0.703 (0.596–0.809) 64.1 73.4 < 0.001  
FBB composite 1.03224 0.708 (0.601–0.814) 82.1 64.1 < 0.001  
DeLong’s test for the two correlated ROC curves
Model 1
  Left parietal SUVR + left precuneus SUVR + FBB composite   0.763 (0.67–0.856) 79.5 67.2 0.002 0.862
Model 2
  Whole VOIs (bilateral temporal, bilateral parietal, left precuneus, left occipital, FBB composite)   0.765 (0.673–0.857) 76.9 68.8 0.002