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Table 3 Volume of the different brain regions between study groups

From: The relationship between retinal layers and brain areas in asymptomatic first-degree relatives of sporadic forms of Alzheimer’s disease: an exploratory analysis

Brain regions

FH– ApoE ε4–

FH+ ApoE ε4+

p-value

Parahippocampal right

1825.89 (211.59)

1902.62 (217.98)

0.187

Parahippocampal left

2053.15 (293.95)

2086.86 (293.95)

0.634

Entorhinal right

2048.11 (286.42)

2120.97 (352.46)

0.402

Entorhinal left

2181.70 (332.07)

2165.55 (308.12)

0.851

Lingual gyrus right

6357.89 (880.20)

6417.83 (1047.83)

0.872

Lingual gyrus left

6004.44 (987.93)

6023.17 (835.08)

0.929

Pericalcarine right

2412.85 (497.76)

2396.17 (466.96)

0.898

Pericalcarine left

2119.63 (452.79)

2142.48 (395.24)

0.841

Lateral occipital right

11,388.93 (1302.19)

11,381.93 (1506.77)

0.985

Lateral occipital left

11,218.59 (1247.33)

11,108.52 (1237.37)

0.742

Cuneus right

3032.56 (442.16)

3095.03 (574.73)

0.652

Cuneus left

2811.04 (450.16)

2874.31 (517.92)

0.629

Medial temporal right

8014.46 (631.63)

8127.23 (761.61)

0.551

Medial temporal left

8158.11 (729.41)

8191.88 (791.15)

0.869

Occipital right

23,210.22 (2589.45)

23,290.97 (2853.82)

0.912

Occipital left

22,153.70 (2482.72)

22,151.48 (2541.49)

0.997

Amygdala right

1502.15 (247.41)

1467.93 (215.52)

0.583

Amygdala left

1298.38 (186.45)

1292.43 (147.13)

0.895

Ventral diencephalon right

3715.45 (349.01)

3701.44 (341.39)

0.880

Ventral diencephalon left

3711.05 (367.22)

3757.41 (386.31)

0.648

Hippocampus right

4140.46 (367.54)

4103.64 (431.50)

0.733

Hippocampus left

3923.25 (346.95)

3939.47 (413.06)

0.875

Intracranial global

1,438,163.2 (162,347.9)

1,415,555.1 (119,222.5)

0.553

  1. Data are expressed as mean and typical deviation. *p < 0.05. Mann–Whitney U test. FH– participants without a family history of AD, FH+ participants with a family history of AD, ApoE ɛ4– noncarriers of ApoE ɛ4, ApoE ɛ4+ carriers of ApoE ɛ4. Measurements are expressed in cubic millimeter