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Table 1 Inclusion criteria for subsamples

From: Cerebrospinal fluid lactate levels along the Alzheimer’s disease continuum and associations with blood-brain barrier integrity, age, cognition, and biomarkers

 

ADD

MCI-AD

FTLD

HC

CSF Aβ42

<650 pg/nl

<650 pg/nl

-

>649 pg/nl

MMSE

<25

>24

-

>27

CSF lactate

<3.5mmol/l

<3.5mmol/l

<3.5mmol/l

<3.5mmol/l

Albumin CSF/serum

<15

<15

<15

<15

Diagnostic criteria

McKhann et al. (29)

Albert et al. (2011)

Rascovsky et al. (2011) Gorno-Tempini et al. (2011)

No subjective cognitive impairment; no neurological/psychiatric diseasea

  1. aIndicated by clinical examination, medical history, and review of patient files
  2. ADD Alzheimer’s disease dementia, MCI-AD mild cognitive impairment due to Alzheimer’s disease, FTLD frontotemporal lobar degeneration, HC healthy controls