Skip to main content
Fig. 1 | Alzheimer's Research & Therapy

Fig. 1

From: Reconfigured metabolism brain network in asymptomatic microtubule-associated protein tau mutation carriers: a graph theoretical analysis

Fig. 1

Hub reconfiguration in asymptomatic MAPT carriers and bvFTD patients. The lost and reconfigured hubs, which were consistently present in asymptomatic MAPT carriers and FTD patients, are shown in the overlap. Yellow circles represent the lost hubs (hubs present in controls but not in asymptomatic MAPT carriers or bvFTD patients); red circles represent the reconfigured hubs (nodes in asymptomatic MAPT carriers or bvFTD patients that assume the role of hubs differ to those in controls); green circles indicate the preserved hubs (hubs present in both asymptomatic MAPT carriers and non-carriers or both bvFTD patients and controls). Hubs were identified as brain regions having a nodal degree centrality one standard deviation higher than the network average. Hubs are represented on a 3D brain template using the BrainNet toolbox

Back to article page

Alzheimer's Research & Therapy

ISSN: 1758-9193