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Table 3 Associations between baseline CIMT and change in cognitive function assessed over 2.5 years from multivariable linear regression models

From: Subclinical carotid artery atherosclerosis and cognitive function in older adults

Cognitive domain β (95% CI)a p-value Model covariates
Executive function − 0.0179 (− 0.0548, 0.0190) 0.34 Baseline executive function composite score, age, sex, race, education, income, marital status, ApoE4 genotype, baseline BMI, baseline SBP, baseline HDL, baseline LDL, current smoking status, study
 < 65 years old − 0.0199 (− 0.0638, 0.0241) 0.37
 ≥ 65 years old − 0.0129 (− 0.0842, 0.0584) 0.72
Verbal memory − 0.0236 (− 0.0793, 0.0321) 0.41 Baseline verbal memory composite score, age, sex, race, education, income, ApoE4 genotype, baseline CES-D score, baseline BMI, baseline SBP, baseline HDL, baseline LDL, current smoking status, study
 < 65 years old − 0.0144 (− 0.0800, 0.0513) 0.67
 ≥ 65 years old − 0.0491 (− 0.1572, 0.0590) 0.37
Visual memory − 0.0231 (− 0.0640, 0.0177) 0.27 Baseline visual memory composite score, age, sex, race, education, income, marital status, baseline BMI, baseline SBP, baseline HDL, baseline LDL, current smoking status, study
 < 65 years old − 0.0356 (− 0.0831, 0.0119) 0.14
 ≥ 65 years old − 0.0160 (− 0.0983, 0.0664) 0.70
Global cognition − 0.0557 (− 0.1103, − 0.0100) 0.046 Baseline global cognition composite score, age, sex, race, education, baseline CES-D score, baseline BMI, baseline SBP, baseline HDL, baseline LDL, current smoking status, study
 < 65 years old − 0.0351 (− 0.1005, 0.0303) 0.29
 ≥ 65 years old − 0.1078 (− 0.2100, − 0.0056) 0.039
  1. aBeta estimates are reported in units per 0.1 mm of CIMT