Table 3 Associations between baseline CIMT and change in cognitive function assessed over 2.5 years from multivariable linear regression models

Executive function

− 0.0179 (− 0.0548, 0.0190)

0.34

Baseline executive function composite score, age, sex, race, education, income, marital status, ApoE4 genotype, baseline BMI, baseline SBP, baseline HDL, baseline LDL, current smoking status, study

 < 65 years old

− 0.0199 (− 0.0638, 0.0241)

0.37

 ≥ 65 years old

− 0.0129 (− 0.0842, 0.0584)

0.72

Verbal memory

− 0.0236 (− 0.0793, 0.0321)

0.41

Baseline verbal memory composite score, age, sex, race, education, income, ApoE4 genotype, baseline CES-D score, baseline BMI, baseline SBP, baseline HDL, baseline LDL, current smoking status, study

 < 65 years old

− 0.0144 (− 0.0800, 0.0513)

0.67

 ≥ 65 years old

− 0.0491 (− 0.1572, 0.0590)

0.37

Visual memory

− 0.0231 (− 0.0640, 0.0177)

0.27

Baseline visual memory composite score, age, sex, race, education, income, marital status, baseline BMI, baseline SBP, baseline HDL, baseline LDL, current smoking status, study

 < 65 years old

− 0.0356 (− 0.0831, 0.0119)

0.14

 ≥ 65 years old

− 0.0160 (− 0.0983, 0.0664)

0.70

Global cognition

− 0.0557 (− 0.1103, − 0.0100)

0.046

Baseline global cognition composite score, age, sex, race, education, baseline CES-D score, baseline BMI, baseline SBP, baseline HDL, baseline LDL, current smoking status, study

 < 65 years old

− 0.0351 (− 0.1005, 0.0303)

0.29

 ≥ 65 years old

− 0.1078 (− 0.2100, − 0.0056)

0.039