Table 2 Costs per year according to the severity of the diagnosis
From: Economic and caregiver impact of Alzheimer’s disease across the disease spectrum: a cohort study
1 year before | First year after | Second year after | |||
|---|---|---|---|---|---|
All patients | N | 1928 | 1998 | 1600 | |
Missing, n | 70 | 0 | 398 | ||
Total costs, € | Mean | 7408 | 9466 | 8870 | |
SD | 14,941 | 17,664 | 15,759 | ||
SE | 340 | 395 | 394 | ||
Median | 2054 | 3444 | 3249 | ||
IQR | 2705 | 4780 | 4843 | ||
Direct medical costs, € | Mean | 7101 | 9103 | 8590 | |
SD | 14,081 | 17,097 | 15,448 | ||
SE | 321 | 383 | 386 | ||
Median | 2014 | 3313 | 3088 | ||
IQR | 2613 | 4674 | 4662 | ||
Direct nonmedical costs (transportation), € | Mean | 307 | 363 | 280 | |
SD | 4132 | 2758 | 2212 | ||
SE | 180 | 102 | 92 | ||
Median | 166 | 288 | 262 | ||
IQR | 254 | 399 | 325 | ||
SCC | n | 619 | 640 | 513 | |
Missing, n | 21 | 0 | 127 | ||
Total costs, € | Mean | 7104 | 8028 | 6196 | |
SD | 14,964 | 15,016 | 11,917 | ||
SE | 601 | 594 | 526 | ||
Median | 1798 | 2576 | 1811 | ||
IQR | 2285 | 3289 | 2915 | ||
Direct medical costs, € | Mean | 6604 | 7581 | 5885 | |
SD | 13,234 | 14,011 | 11,365 | ||
SE | 532 | 554 | 502 | ||
Median | 1764 | 2532 | 1802 | ||
IQR | 2128 | 3223 | 2747 | ||
Direct nonmedical costs (transportation), € | Mean | 500 | 447 | 310 | |
SD | 5941 | 3678 | 3150 | ||
SE | 480 | 261 | 268 | ||
Median | 153 | 266 | 233 | ||
IQR | 227 | 433 | 240 | ||
MCI | n | 610 | 630 | 511 | |
Missing, n | 20 | 0 | 119 | ||
Total costs, € | Mean | 7899 | 9758 | 8452 | |
SD | 15,626 | 18,297 | 14,291 | ||
SE | 633 | 729 | 632 | ||
Median | 2160 | 3486 | 3286 | ||
IQR | 2588 | 4672 | 4639 | ||
Direct medical costs, € | Mean | 7596 | 9361 | 8130 | |
SD | 14,946 | 17,665 | 13,849 | ||
SE | 605 | 704 | 613 | ||
Median | 2130 | 3329 | 3073 | ||
IQR | 2563 | 4591 | 4180 | ||
Direct nonmedical costs (transportation), € | Mean | 303 | 397 | 323 | |
SD | 4143 | 3088 | 2553 | ||
SE | 310 | 194 | 183 | ||
Median | 185 | 357 | 309 | ||
IQR | 310 | 452 | 447 | ||
Mild AD dementia | n | 204 | 212 | 173 | |
Missing, n | 8 | 0 | 39 | ||
Total costs, € | Mean | 8022 | 10,558 | 13,717 | |
SD | 18,658 | 18,583 | 24,093 | ||
SE | 1306 | 1276 | 1832 | ||
Median | 2370 | 5136 | 5512 | ||
IQR | 2861 | 5275 | 4695 | ||
Direct medical costs, € | Mean | 7889 | 10,244 | 13,462 | |
SD | 18,426 | 18,317 | 23,946 | ||
SE | 1290 | 1258 | 1821 | ||
Median | 2358 | 4765 | 5512 | ||
IQR | 2867 | 5434 | 4835 | ||
Direct nonmedical costs (transportation), € | Mean | 133 | 314 | 254 | |
SD | 755 | 1088 | 909 | ||
SE | 101 | 115 | 106 | ||
Median | 187 | 294 | 283 | ||
IQR | 324 | 462 | 274 | ||
Moderate AD dementia | n | 242 | 256 | 208 | |
Missing, n | 14 | 0 | 48 | ||
Total costs, € | Mean | 6081 | 10544 | 9783 | |
SD | 10,362 | 18,688 | 14,155 | ||
SE | 666 | 1168 | 981 | ||
Median | 2047 | 4384 | 4145 | ||
IQR | 3682 | 5672 | 6257 | ||
Direct medical costs, € | Mean | 5977 | 10,256 | 9589 | |
SD | 10,167 | 18,377 | 13,993 | ||
SE | 654 | 1149 | 970 | ||
Median | 2018 | 4292 | 4095 | ||
IQR | 3682 | 5856 | 6446 | ||
Direct nonmedical costs (transportation), € | Mean | 104 | 288 | 193 | |
SD | 811 | 1349 | 847 | ||
SE | 98 | 140 | 98 | ||
Median | 102 | 263 | 280 | ||
IQR | 103 | 325 | 297 | ||
Moderately severe/severe AD dementia | n | 253 | 260 | 195 | |
Missing, n | 7 | 0 | 65 | ||
Total costs, € | Mean | 7740 | 10,345 | 11,728 | |
SD | 13,483 | 20,077 | 18,903 | ||
SE | 848 | 1245 | 1354 | ||
Median | 2212 | 4130 | 4993 | ||
IQR | 4613 | 6323 | 8169 | ||
Direct medical costs, € | Mean | 7563 | 10,161 | 11,525 | |
SD | 13,090 | 19,914 | 18,810 | ||
SE | 823 | 1235 | 1347 | ||
Median | 2207 | 4125 | 4448 | ||
IQR | 4603 | 6222 | 7857 | ||
Direct nonmedical costs (transportation), € | Mean | 178 | 184 | 203 | |
SD | 1975 | 1042 | 615 | ||
SE | 238 | 109 | 64 | ||
Median | 212 | 229 | 213 | ||
IQR | 230 | 236 | 217 | ||
P value* | 0.096 | 0.004 | < .0001 | ||
P value† | 0.487 | 0.225 | < .0001 | ||