Fig. 1

Kaplan-Meier estimates of mutation carriers that converted from CDR® plus NACC FTLD 0.5 to ≥ 1. The number of mutation carriers included, and the number that progressed or were lost to follow-up are reported in Additional file 1: Table S4. C9orf72, chromosome 9 open reading frame 72; GRN, progranulin; MAPT, microtubule-associated protein tau; CDR plus NACC FTLD, Clinical Dementia Rating scale plus National Alzheimer’s Coordinating Center Frontotemporal Lobar Degeneration