Skip to main content

Table 4 Mean (SD) 2FA binding (VT/fp) within the AD and MCI groups, for those on and off AChEI medication

From: Cholinergic receptor binding in unimpaired older adults, mild cognitive impairment, and Alzheimer’s disease dementia

Variable

MCI

AD

Off aAChEI (n = 20)

Ona AChEI (n = 8)

Off AChEI (n = 9)

On AChEI (n = 23)

L thalamus

12.25 (1.76)

11.91 (2.50)

12.96 (1.57)b

10.94 (1.98)

R thalamus

12.42 (1.64)

12.28 (2.62)

13.12 (1.53)b

11.17 (2.34)

L hippocampus

7.15 (.83)

7.63 (1.20)

7.50 (.84)b

5.88 (1.19)

R hippocampus

7.18 (.80)

7.44 (1.30)

7.34 (.82)b

6.14 (.93)

L caudate

5.92 (1.62)

5.16 (2.28)

5.40 (1.85)

4.46 (1.91)

R caudate

6.15 (1.52)

5.50 (1.39)

5.90 (1.64)

4.31 (2.11)

L entorhinal

8.55 (1.22)

8.51 (1.28)

8.51 (.87)

8.48 (1.77)

R entorhinal

10.21 (1.35)

10.51 (2.01)

10.13 (1.11)

9.67 (2.48)

L insula

8.22 (.95)

8.93 (1.01)

8.67 (1.16)

7.87 (1.39)

R insula

8.44 (.80)

8.95 (1.07)

8.72 (1.38)

8.00 (1.05)

L anterior cingulate

10.17 (1.20)

10.63 (1.76)

10.71 (1.43)

10.15 (1.93)

R anterior cingulate

10.22 (1.15)

10.47 (1.55)

10.70 (1.43)

9.68 (2.22)

  1. aOff and on refers to the current use of cholinesterase inhibitor medication
  2. bSignificant difference within the diagnostic group, p < .05