| |
Cases
|
Controls
|
|---|
|
All
|
Female
|
Male
|
All
|
Female
|
Male
|
|---|
|
N
|
202
|
133
|
69
|
166
|
110
|
56
|
|
Age (years)
|
75.8 ± 4.4
|
76.1 ± 4.4
|
75.2 ± 4.5
|
75.1 ± 4.1
|
75.5 ± 4.0
|
74.4 ± 4.2
|
|
Sex (% female)
|
65.8
|
-
|
-
|
66.3
|
-
|
-
|
|
Education level, ≥ secondary school (%)
|
29.7
|
30.1
|
29.0
|
31.9
|
31.8
|
32.1
|
|
ApoE-ε4+ frequency (%)
|
25.7
|
25.6
|
26.1
|
12.0
|
13.6
|
8.9
|
|
BMI (kg m-2)
|
26.8 ± 4.3
|
26.4 ± 4.6
|
27.6 ± 3.7
|
26.3 ± 3.7
|
26.1 ± 4.2
|
26.7 ± 2.6
|
|
Number of medications regularly consumed
|
4.9 ± 2.8
|
5.2 ± 2.7
|
4.2 ± 2.7
|
3.9 ± 2.3
|
4.1 ± 2.1
|
3.4 ± 2.7
|
|
MMSE (points)
|
27.0 ± 2.2
|
27.0 ± 2.2
|
26.9 ± 2.2
|
27.9 ± 1.7
|
27.8 ± 1.8
|
28.2 ± 1.4
|
|
BVRT (points)
|
10.8 ± 2.1
|
10.6 ± 2.1
|
11.1 ± 2.1
|
11.8 ± 1.9
|
11.6 ± 2.0
|
12.2 ± 1.7
|
|
IST (points)
|
27.8 ± 5.8
|
27.7 ± 5.7
|
28.0 ± 6.4
|
31.2 ± 6.1
|
31.2 ± 6.4
|
31.1 ± 5.7
|
|
TMTA (number of correct displacements per minute)
|
24.1 ± 8.0
|
23.5 ± 7.7
|
25.4 ± 8.5
|
29.3 ± 9.3
|
29.1 ± 9.3
|
29.7 ± 9.4
|
|
TMTB (number of correct displacements per minute)
|
10.0 ± 5.8
|
9.8 ± 5.5
|
10.6 ± 6.5
|
14.5 ± 6.7
|
14.4 ± 6.7
|
14.8 ± 6.6
|
|
Glucose (mmol L-1)
|
5.5 ± 1.6
|
5.4 ± 1.8
|
5.5 ± 1.3
|
5.1 ± 1.0
|
4.9 ± 0.7
|
5.6 ± 1.4
|
|
Creatinine (mmol L-1)
|
83.1 ± 22.5
|
75.9 ± 14.2
|
97.0 ± 28.3
|
79.3 ± 18.1
|
73.6 ± 14.9
|
90.7 ± 18.5
|
|
Cholesterol (mmol L-1)
|
5.8 ± 0.9
|
5.9 ± 0.9
|
5.6 ± 0.9
|
5.8 ± 1.0
|
5.9 ± 1.0
|
5.7 ± 0.9
|
|
LDL-C (mmol L-1)
|
3.6 ± 0.8
|
3.7 ± 0.8
|
3.6 ± 0.8
|
3.6 ± 0.9
|
3.7 ± 1.0
|
3.6 ± 0.7
|
|
HDL-C (mmol L-1)
|
1.6 ± 0.4
|
1.7 ± 0.4
|
1.4 ± 0.4
|
1.6 ± 0.4
|
1.6 ± 0.4
|
1.4 ± 0.3
|
|
Triglycerides (mmol L-1)
|
1.4 ± 0.8
|
1.3 ± 0.7
|
1.4 ± 0.9
|
1.3 ± 0.7
|
1.2 ± 0.5
|
1.4 ± 0.9
|
- Abbreviations: ApoE-ε4+, carrier of the ε4 allele of the apolipoprotein E gene; BMI, body mass index; MMSE, Mini-Mental State Examination test; BVRT, Benton Visual Retention Test; IST, Isaac’s Set Test; TMTA, Trail-Making Test part A; TMTB, Trail-Making Test part B; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol.
