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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Comparison of plasma neurofilament light and total tau as neurodegeneration markers: associations with cognitive and neuroimaging outcomes

Fig. 3

Cross-sectional and longitudinal associations between plasma biomarkers and cognitive and imaging outcomes in ADNI. Relationships between plasma NfL or T-tau and cognition or neuroimaging in ADNI. A Associations at cross-section. B Associations over time (median follow-up 3.0 years). For the ADAS-Cog13 and Trail Making Test B, a higher score indicates worse performance. Models adjust for age, sex, and education. Hippocampal volume measures were adjusted for total intracranial volume. Abbreviations: ADAS Alzheimer’s disease assessment scale-cognitive subscale 13 tasks, ADNI Alzheimer’s Disease Neuroimaging Initiative, TMTB Trail Making Test Part B

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Alzheimer's Research & Therapy

ISSN: 1758-9193