Table 2 Multilevel univariable and multivariable logistic regressions predicting likelihood of disease progression^a

Age, years

1.00 (0.97 to 1.03)

0.927

–

–

Male sex (vs female)

0.72 (0.42 to 1.23)

0.225

–

–

Education, years

1.01 (0.94 to 1.09)

0.769

–

–

Genetic mutation (vs sporadic)

1.82 (0.86 to 3.85)

0.115

–

–

bvFTD (vs PPA)

1.30 (0.72 to 2.33)

0.387

–

–

Disease duration

1.02 (0.91 to 1.16)

0.711

–

–

Serum NfL, pg/mL

1.07 (1.03 to 1.11)

< 0.001

1.08 (1.03 to 1.13)

0.003

MMSE score

0.93 (0.88 to 0.99)

0.020

0.79 (0.64 to 0.99)

0.040

FBI score

1.05 (1.02 to 1.08)

0.004

1.13 (1.03 to 1.24)

0.008

BADL lost

1.22 (0.77 to 1.90)

0.391

–

–

IADL lost

1.16 (0.95 to 1.41)

0.149

–

–

Digit span

0.84 (0.68 to 1.03)

0.098

–

–

Trail making test part A

1.00 (1.00 to 1.01)

0.029

1.00 (1.00 to 1.01)

0.362

Trail making test part B

1.00 (1.00 to 1.00)

0.015

1.00 (1.00 to 1.01)

0.485