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Table 1 Demographics of study samples

From: Dysregulated expression levels of APH1B in peripheral blood are associated with brain atrophy and amyloid-β deposition in Alzheimer’s disease

Cohort

Diagnosis

N

Female (%)

Age at blood sample collection, mean (SD)

RIN, mean (SD)

ADNI (N = 661)

CN

213

107 (50%)

76.4 (6.4)

6.91 (0.51)

MCI

345

144 (42%)

73.2 (7.9)

6.98 (0.55)

AD

103

38 (37%)

77.6 (7.8)

6.98 (0.64)

AddNeuroMed (N = 674)

CN

243

147 (60%)

74.2 (6.6)

8.96 (0.73)

MCI

208

120 (58%)

75.5 (6.5)

8.50 (0.59)

AD

223

146 (65%)

76.8 (6.8)

8.43 (0.64)

  1. The table was modified from a previous study [51]
  2. Abbreviations: AD Alzheimer’s disease; CN cognitively normal older adults; MCI mild cognitive impairment; RIN RNA integrity number; SD standard deviation