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Table 6 Top 44 (top 20%) predicted microbial metabolites for the combined input “microgliosis,” “abnormal microglial cell physiology,” and “abnormal microglial cell morphology”

From: Gut–microbiota–microglia–brain interactions in Alzheimer’s disease: knowledge-based, multi-dimensional characterization

R Metabolite R Metabolite R Metabolite R Metabolite
1 Acetic acid 12 Ascorbic acid 23 Butyric acid 34 Sulfamethoxazole n1-glucuronide
2 Ethanol 13 Mannitol 24 Isopropyl alcohol 35 Salicyluric acid
3 d-Alanine 14 Epinephrine 25 Serotonin 36 Propionic acid
4 d-Glutamic acid 15 Methane 26 Folic acid 37 d-Proline
5 Hydrogen 16 Norepinephrine 37 Phenylethylamine 38 3-Hydroxydodecanoic acid
6 Dopamine 17 Gamma-aminobutyric acid 28 2-Phenylethanaminium 39 1-Butanol
7 d-Lactic acid 18 4-Hydroxybutyric acid 29 Phenol 40 3-Hydroxybutyric acid
8 l-Lactic acid 19 Oxoglutaric acid 30 Chenodeoxycholic acid 3-sulfate 41 Zeaxanthin
9 Hydroxypropionic acid 20 Glutaric acid 31 3,4-Dihydroxybenzeneacetic acid 42 Cis,cis-muconic acid
10 Acetaldehyde 21 Melatonin 32 Succinic acid 43 Trans-trans-muconic acid
11 Histamine 22 Trehalose 33 Muramic acid 44 Nndole