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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: Performance of the plasma Aβ42/Aβ40 ratio, measured with a novel HPLC-MS/MS method, as a biomarker of amyloid PET status in a DPUK-KOREAN cohort

Fig. 3

Scatterplot of plasma Aβ42/Aβ40 and Aβ PET centiloid in the A total, B OC, C aMCI, and D ADD groups. The dashed red lines indicate cutoffs for plasma Aβ42/Aβ40 (0.2576) based on the maximum Youden index and for Aβ PET centiloids (25.11) for amyloid PET positivity. The cutoff value of PET centiloid and Aβ42/Aβ40 were 25.11 and 0.2576, respectively. Abbreviations: total, total participants excluding YCs; OC, old controls; aMCI, amnestic mild cognitive impairment; ADD, Alzheimer’s disease dementia; SVCI, subcortical vascular cognitive impairment; CAA, cerebral amyloid angiopathy; YC, young controls; PET, positron emission tomography

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Alzheimer's Research & Therapy

ISSN: 1758-9193