Skip to main content

Table 1 Demographics, clinical characteristics, and biomarker information of the study population

From: A cross-sectional study in healthy elderly subjects aimed at development of an algorithm to increase identification of Alzheimer pathology for the purpose of clinical trial participation

Characteristics Total group, n = 154 Amyloid status CSF
Aβ positive, n = 42 (27.3%) Aβ negative, n = 112 (72.7%)
Age, years 72.1 [65; 86] 73.7 [65; 85] 71.4 [65; 86]
Female gender 49 (31.8 %) 13 (30.6%) 36 (32.1%)
MMSE 29 (25–30) 29 (25–30) 29 (25–30)
GDS 0 (0–5) 1 (0–5) 0 (0–5)
CDR 0.0 (0–0.5) 0.0 (0) 0.0 (0–0.5)
IADL 0.0 (0) 0.0 (0) 0.0 (0)
Educationa 6 (1–7) 6 (1–7) 6 (1–7)
Apoe e4/e4 (n = 150) 5 (3.3%) 5 (100%) 0 (0%)
Apoe at least one e4 allele (n = 150) 39 (26%) 18 (42.9%) 21 (18.8%)
  1. Continuous data are presented as mean [min; max] and dichotomous data as n (%). MMSE, Mini Mental State Examination; GDS, Geriatric Depression Scale; CDR, Clinical Dementia rating Scale; IADL, Instrumental Activity of Daily Living scale; Apoe e4, apolipoprotein E 4.
  2. aLevel of education defined as (1) lower than primary school, (2) primary school, (3) less than lower professional education, (4) lower professional education, (5) mid-level professional education, (6) high school/college, and (7) university