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Table 1 Demographics, clinical characteristics, and biomarker information of the study population

From: A cross-sectional study in healthy elderly subjects aimed at development of an algorithm to increase identification of Alzheimer pathology for the purpose of clinical trial participation

Characteristics

Total group, n = 154

Amyloid status CSF

Aβ positive, n = 42 (27.3%)

Aβ negative, n = 112 (72.7%)

Age, years

72.1 [65; 86]

73.7 [65; 85]

71.4 [65; 86]

Female gender

49 (31.8 %)

13 (30.6%)

36 (32.1%)

MMSE

29 (25–30)

29 (25–30)

29 (25–30)

GDS

0 (0–5)

1 (0–5)

0 (0–5)

CDR

0.0 (0–0.5)

0.0 (0)

0.0 (0–0.5)

IADL

0.0 (0)

0.0 (0)

0.0 (0)

Educationa

6 (1–7)

6 (1–7)

6 (1–7)

Apoe e4/e4 (n = 150)

5 (3.3%)

5 (100%)

0 (0%)

Apoe at least one e4 allele (n = 150)

39 (26%)

18 (42.9%)

21 (18.8%)

  1. Continuous data are presented as mean [min; max] and dichotomous data as n (%). MMSE, Mini Mental State Examination; GDS, Geriatric Depression Scale; CDR, Clinical Dementia rating Scale; IADL, Instrumental Activity of Daily Living scale; Apoe e4, apolipoprotein E 4.
  2. aLevel of education defined as (1) lower than primary school, (2) primary school, (3) less than lower professional education, (4) lower professional education, (5) mid-level professional education, (6) high school/college, and (7) university