Table 3 Baseline and 4-year remote follow-up neurologic, neurocognitive, functional, and health assessments

Neurologic exam

Semi-structured clinical examination of cranial nerves, sensory functions, muscle strength, fasciculations, and reflexes

I

–

Motor

International Parkinson and Movement Disorder Society-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS) [101]

I

V

Timed Up and Go (TUG) [102]

I

–

Effort (symptom validity)

Test of Memory Malingering (TOMM) [103] [104]

I

V

Estimated premorbid intelligence

Wide Range Achievement Test-Fourth Edition (WRAT-4) Word Reading []

I

–

Cognitive screening

Montreal Cognitive Assessment (MoCA) [106, 107]

I

T,V

Attention, visual scanning, and psychomotor speed

Symbol Digit Modalities Test [108]

I

V

Trail Making Test Part A [109]

I

–

Unified Data Set (UDS) Number Span Test [110]

I

T

Executive function

Behavior Rating Inventory of Executive Function-Adult Version (BRIEF-A) Global Executive Composite (GEC; Participant and Informant) [111]

R

R

BRIEF-A Metacognition Index (MI; Participant and Informant) [111]

R

R

Phonemic Fluency - Controlled Oral Word Association Test (COWAT) [112]

I

T

Golden Stroop Color and Word Interference [98]

I

–

Neuropsychological Assessment Battery (NAB) Mazes [99, 113]

I

–

Trail Making Test Part B [109]

I

–

NAB Categories [99]

–

V

Cambridge Neuropsychological Test Automated Battery (CANTAB) One Touch Stockings of Cambridge (OTS) [114, 115]

–

C

CANTAB Spatial Working Memory (SWW) [114, 115]

–

C

CANTAB Cambridge Gambling Task (CGT) [114, 115]

–

C

Learning and memory

Brief Visuospatial Memory Test – Revised (BVMT-R) [104]

I

V

UDS Craft Story [110]

I

T

NAB List Learning [99]

I

T

CANTAB Paired Associate Learning (PAL) [114, 115]

–

C

CANTAB Pattern Recognition Memory (PRM) [114, 115]

–

C

Language

Category (Semantic) Fluency - Animals [112, 116]

I

T

Category (Semantic) Fluency - Vegetables [112, 116]

–

T

UDS Multilingual Naming Test (MINT) [110]

I

V

Visuospatial ability

Judgment of Line Orientation (JOLO) [117]

I

V

BVMT-R Copy [104]

I

V

Emotional facial perception

CANTAB Emotional Recognition Task (ERT) [114, 115]

–

C

Dementia severity

Functional Activities Questionnaire (FAQ; Participant and Informant) [118]

R

R

Quick Dementia Rating System (QDRS; Participant and Informant) [119]

R

R

Sleep

Mayo Sleep Questionnaire (MSQ; Participant and Informant) [120]

R

R

Epworth Sleepiness Scale [121]

R

R

Olfactory

Brief Smell Identification Test (B-SIT) [122]

I

–

Pain

Headache Impact Test (HIT-6) [123]

R

R

Brief Pain Inventory (BPI) [124, 125]

P

P

Substance use

Alcohol Use Disorders Identification Test: Interview Version (AUDIT) [126]

I

T

Modified National Institute on Drug Abuse (NIDA) Alcohol, Smoking and Substance Involvement Screening Test (ASSIST) version 2.0 [127]

I

T

Health status

EQ-5D-5L Health Questionnaire [128]

P

P

National Health and Nutrition Examination Survey (NHANES) Physical Activity and Physical Fitness Questionnaire (PAQ) [129]

I

T

NHANES Weight History Questionnaire [130]

I

T