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Table 2 DEmiRNAs reported by the included differential miRNA expression studies. The bold DEmiRNAs were reported by at least two independent comparisons and were qualified for the subsequent meta-analysis

From: Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learning

Comparison ID MiRNAs Dysregulated direction P value
31857133_Ser miR-193a-3p Down < 0.001
31811079_Ser miR-346 Up 0.0013
miR-345-5p Up 0.0239
miR-122-3p Up 0.0001
miR-1291 Up 0.0052
miR-640 Up 0.0004
miR-650 Up 0.0035
miR-1285-3p Up 0.0032
miR-1299 Up 0.0003
miR-1267 Up 0.0055
miR-208b-3p Down 0.0006
miR-206 Down 0.0004
31849573_Pla miR-132-3p Down 0.0333
miR-212-3p Down 0.001
31809862_WB miR-532-5p Up 4.8 × 10E−30
miR-1468-5p Down 6.2 × 10E−12
31766231_Pla miR-206 Up < 0.025
31691877_Ser miR-22-5p Up ≤ 0.005
miR-23a-3p Up ≤ 0.05
miR-29a-3p Up ≤ 0.05
miR-125b-5p Up ≤ 0.005
31592314_Pla miR-451a Down < 0.0005
miR-21-5p Down < 0.005
miR-23a-3p Down < 0.005
let-7i-5p Down < 0.05
miR-126-3p Down < 0.005
miR-151a-3p Down < 0.05
31572518_Ser miR-133b Down < 0.001
31420923_Pla miR-103a-3p Down < 0.001
miR-107 Down < 0.001
31092279_Pla miR-92a-3p Up 0.0442
miR-181c-5p Up 0.0024
miR-210-3p Up 0.0006
30914454_Pla miR-101-3p Down < 0.001
miR-153-3p Down < 0.001
miR-144-3p Down < 0.001
miR-381-3p Down < 0.001
miR-383-5p Down < 0.001
30328325_Pla miR-128-3p Up < 0.05
29966198_Pla miR-146a-5p Up < 0.05
miR-933 Up < 0.05
29746584_Ser miR-103a-3p Up < 0.05
miR-142-3p Up < 0.05
miR-20a-5p Up < 0.05
miR-29b-3p Up < 0.05
let-7b-5p Up < 0.05
let-7 g-5p Up < 0.05
miR-106a-5p Up < 0.05
miR-106b-5p Up < 0.05
miR-18b-5p Up < 0.05
miR-223-3p Up < 0.05
miR-26a-5p Up < 0.05
miR-26b-5p Up < 0.05
miR-301a-3p Up < 0.05
miR-30b-5p Up < 0.05
miR-132-3p Down < 0.05
miR-146a-5p Down < 0.05
miR-15a-5p Down < 0.05
miR-22-3p Down < 0.05
miR-320a-3p Down < 0.05
miR-320b Down < 0.05
miR-92a-3p Down < 0.05
miR-1246 Down < 0.05
29635818_Pla miR-1908-5p Up < 0.05
29606187_Ser miR-135a-5p Up < 0.05
miR-193b-3p Down < 0.01
miR-384 Up < 0.05
29036829_WB miR-144-5p Down 0.03
miR-374a-5p Down 0.034
miR-221-3p Down 0.042
29036818_Ser_Mild miR-106b-3p Up < 0.001
miR-26a-5p Down < 0.001
miR-181c-3p Down < 0.001
miR-126-5p Down < 0.001
miR-22-3p Down < 0.001
miR-148b-5p Down < 0.001
29036818_Ser_Mod miR-106b-3p Up < 0.001
miR-1246 Up < 0.001
miR-26a-5p Down < 0.001
miR-181c-3p Down < 0.001
miR-126-5p Down < 0.001
miR-22-3p Down < 0.001
miR-148b-5p Down < 0.001
29036818_Ser_Sev miR-106b-3p Up < 0.001
miR-1246 Up < 0.001
miR-660-5p Up < 0.001
miR-26a-5p Down 0.007
miR-181c-3p Down < 0.001
miR-126-5p Down < 0.001
miR-22-3p Down < 0.001
miR-148b-5p Down < 0.001
28934394_Ser miR-455-3p Up 0.007
28849039_Ser_Mil miR-222-3p Down < 0.05
28849039_Ser_Mod miR-222-3p Down < 0.05
28626163_Ser miR-146a-5p Up < 0.05
miR-106b-3p Up < 0.05
miR-195-5p Up < 0.05
miR-20b-5p Up < 0.05
miR-497-5p Up < 0.05
miR-29c-3p Down < 0.05
miR-93-5p Down < 0.05
miR-19b-3p Down < 0.05
miR-125b-3p Down < 0.05
28179587_Pla_AD2 miR-486-5p Up < 0.001
miR-483-5p Up < 0.0001
miR-502-3p Up < 0.0001
miR-200a-3p Up < 0.01
miR-151a-5p Down < 0.001
miR-30b-5p Down < 0.01
miR-103a-3p Down < 0.01
28179587_Pla_MCI-AD2 miR-486-5p Up < 0.001
miR-483-5p Up < 0.001
miR-502-3p Up < 0.01
miR-200a-3p Up < 0.05
28137310_Ser miR-501-3p Down 0.002
27545218_Ser miR-613 Up < 0.01
27501295_WB miR-9-5p Down 0.001
miR-106a-5p Down 0.001
miR-106b-5p Down 0.008
miR-107 Down 0.001
27446280_WB miR-135b-5p Down < 0.01
27277332_WB miR-206 Up < 0.001
27239545_PBMC miR-27b-3p Up < 0.05
miR-128-3p Up < 0.05
miR-155-5p Up < 0.05
27027823_Ser miR-125b-5p Down < 0.001
miR-223-3p Down < 0.001
miR-29 Down < 0.01
miR-519 Up < 0.001
26973465_Pla miR-10b-5p Down 0.022
miR-29a-3p Down 0.041
miR-130b-3p Down 0.002
26497032_PBMC miR-425-5p Up < 0.001
miR-339-5p Up 0.003
miR-639 Down 0.04
26078483_Ser miR-31-5p Down < 0.0001
miR-93-5p Down < 0.0001
miR-143-3p Down < 0.0001
miR-146a-5p Down < 0.0001
25955795_WB miR-29c-3p Down 0.0001
25742200_Pla miR-107 Down < 0.001
25667669_Ser miR-210-3p Down < 0.01
25152461_Ser miR-135a-5p Down < 0.05
miR-200b-3p Down < 0.05
24827165_Pla miR-384 Down < 0.05
24827165_Ser miR-384 Down < 0.05
24577456_Ser miR-98-5p Down 2.67 × 10E−4
miR-885-5p Down 2.8 × 10E−4
miR-483-3p Down 1.0 × 10E−4
miR-342-3p Down 9.19 × 10E−16
miR-191-5p Down 1.54 × 10E−9
let-7d-5p Down 1.2 × 10E−6
24550773_Pla miR-34c-5p Up < 0.01
24550773_PBMC miR-34c-5p Up < 0.01
24157723_Pla miR-34a-5p Down < 0.05
miR-146a-5p Down < 0.05
24139697_Ser miR-125b-5p Down < 0.0001
miR-181c-5p Down < 0.0001
miR-9-5p Up 0.0045
24064186_PBMC_Mon miR-128-3p Up < 0.05
24064186_PBMC_Lym miR-128-3p Up < 0.05
23922807_Pla_C2 let-7d-5p Down 0.0001
let-7 g-5p Down 0.001
miR-15b-5p Down 0.001
miR-142-3p Down 0.0001
miR-191-5p Down 0.002
miR-545-3p Down 0.03
23895045_WB miR-151a-3p Up < 0.05
let-7d-3p Up < 0.05
miR-5010-3p Up < 0.05
let-7f-5p Down < 0.05
miR-1285-5p Down < 0.05
miR-107 Down < 0.05
miR-103a-3p Down < 0.05
miR-26b-5p Down < 0.05
miR-26a-5p Down < 0.05
miR-532-5p Down < 0.05
23435408_PBMC miR-29b-3p Down 0.002
22155483_Ser miR-137-3p Down < 0.05
miR-181c-5p Down < 0.05
miR-9-5p Down < 0.05
miR-29a-3p Down < 0.05
miR-29b-3p Down < 0.05
19936094_PBMC miR-34a-5p Up < 0.05
miR-181b-5p Up < 0.05