Fig. 3From: A phase 2 double-blind placebo-controlled 24-week treatment clinical study of the p38 alpha kinase inhibitor neflamapimod in mild Alzheimer’s diseaseRelationship between Ctrough and episodic memory measures. Plasma trough drug concentration in neflamapimod versus change from baseline to week 24. a HVLT-R combined total and delayed recall Z-score (i.e., primary endpoint), and b WMS combined immediate and delayed recall composite is shown in circles (open for treatment-naïve subjects, closed for those on background AD therapy). For comparison, placebo subjects are shown in triangles (open for treatment-naïve subjects, closed for those on background AD therapy) on the left side of the figureBack to article page