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Table 2 Patient demographics of the cohort that was prospectively studied for the neurologist’s perceived usefulness of biomarker sNfL

From: A neurologist’s perspective on serum neurofilament light in the memory clinic: a prospective implementation study

 

Total

n

109

Age, mean (SD)

63 (9)

Sex = f, n (%)

44 (40)

MMSE, median [IQR]

26 [23, 28]

CSF biomarkers available = Y (%)

76 (69)

Doubt diagnosis = yes (%)

18 (17)

Diagnosis, n (%)

 Subjective cognitive decline (SCD)

28 (26)

 Mild cognitive impairment (MCI), of which 3 due to AD, 2 clinically defined

5 (5)

 Dementia due to AD

29 (27)

 Other dementia (OD)

11 (10)

 Other neurology (ON)

11 (10)

 Psychiatric disorder

17 (16)

 Postponed

8 (7)

aβ1-42, pg/mL (median [IQR])

889 [559, 1446]

pTau, pg/mL (median [IQR])

16 [11, 26]

tTAU, pg/mL (median [IQR])

200 [135, 290]

sNfL, pg/mL (median [IQR])

14 [10, 19]

  1. Variables are represented as number (percentage) or as median [interquartile range] concentration in pg/mL
  2. Abbreviations: amyloid-beta1-42: aβ1-42; CSF: cerebrospinal fluid; MMSE: Mini Mental State Examination; pTau: phosphorylated Tau; sNfL: serum Neurofilament Light; tTau: total Tau