Table 1 Demographics of the ADNI and UPenn datasets
From: Pathological drivers of neurodegeneration in suspected non-Alzheimer’s disease pathophysiology
ADNI | UPenn | |||||
|---|---|---|---|---|---|---|
A−N− | SNAP | A+N+ | A−N− | SNAP | A+N+ | |
Number (%) | 6 (9.5) | 14 (22.2) | 35 (55.6) | 11 (7.1) | 47 (30.1) | 76 (48.7) |
Age at death (years) | 84.5±3.8 | 83.6±8.4 | 82.0±6.9 | 68.6±5.9 | 68.9±9.8 | 74.2±11.8* |
Gender (% male) | 4 (66.7)◊ | 14 (100) | 27 (77.1)◊ | 8 (72.7) | 47 (61.8) | 26 (55.3) |
Time difference between MRI and date of death (years) | 4.5±2.1 | 5.9±2.8 | 4.3±2.5◊ | 2.1±2.5 | 2.1±2.0 | 3.2±2.5* |
Clinical diagnosis at MRI | ||||||
Control (%) | 4 (66.7) | 1 (7.1) | 2 (5.7) | 0 (0) | 0 (0) | 0 (0) |
MCI (%) | 2 (33.3) | 11 (78.6) | 16 (45.7) | 0 (0) | 1 (2.1) | 6 (7.9) |
Dementia (%) | 0 (0) | 2 (14.3) | 17 (48.6) | 11 (100) | 46 (97.9) | 69 (90.8) |
Others (%) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 1 (1.3)a |
Latest clinical diagnosis | ||||||
Control (%) | 3 (50.0) | 1 (7.1) | 0 (0) | 0 (0) | 0 (0) | 0 (0) |
MCI (%) | 2 (33.3) | 2 (14.3) | 4 (11.4) | 0 (0) | 1 (2.1) | 4 (5.3) |
Dementia (%) | 1 (16.7) | 3 (78.6) | 31 (88.6) | 11 (100) | 46 (97.9) | 72 (94.7) |