Table 1 Characteristics of dementia-free participants having at least one outcome of interest
From: Investigating the relationship between BMI across adulthood and late life brain pathologies
Variable | N men/women (total) | Value in men and women combined | |
|---|---|---|---|
Age at assessment, mean (SD) | 238/227 (465) | 70.7 (0.7) | |
Age at scanning, mean (SD) | 238/227 (465) | 70.7 (0.7) | |
β-Amyloid positive, n (%) | 232/225 (457) | 83 (18.2) | |
Whole brain volume in ml, mean (SD) | 227/218 (445) | 1100.0 (98.4) | |
Mean hippocampal volume in ml, mean (SD) | 227/218 (445) | 3.1 (0.3) | |
White matter hyperintensity volume in ml, median (IQR) | 233/220 (453) | 3.1 (1.6, 6.8) | |
Total intracranial volume in ml, mean (SD) | 233/220 (453) | 1434.0 (132.3) | |
MMSE/30, mean (SD) | 238/227 (465) | 29.3 (0.9) | |
BMI at 36 years in kg/m2, mean (SD) | 217/209 (426) | 23.7 (3.1) | |
BMI at 43 years in kg/m2, mean (SD) | 231/215 (446) | 24.9 (3.2) | |
BMI at 53 years in kg/m2, mean (SD) | 232/224 (456) | 26.9 (4.1) | |
BMI at 60–64 years in kg/m2, mean (SD) | 238/227 (465) | 27.5 (4.1) | |
BMI at 69 years in kg/m2, mean (SD) | 236/222 (458) | 27.6 (4.4) | |
BMI at 71 years in kg/m2, mean (SD) | 238/227 (465) | 27.6 (4.4) | |
AC at 36 years in cm, mean (SD) | 217/209 (426) | 81.7 (11.0) | |
AC at 43 years in cm, mean (SD) | 230/218 (448) | 83.0 (11.2) | |
AC at 53 years in cm, mean (SD) | 232/225 (457) | 90.4 (12.0) | |
AC at 60–64 years in cm, mean (SD) | 238/227 (465) | 95.5 (11.7) | |
AC at 69 years in cm, mean (SD) | 236/223 (459) | 95.1 (12.3) | |
Weight category at age 36, n (%) | Underweight | 217/209 (426) | 9 (2.1) |
Normal weight | 303 (71.1) | ||
Overweight | 101 (23.7) | ||
Obese | 13 (3.1) | ||
Weight category at age 43, n (%) | Underweight | 231/215 (446) | 3 (0.7) |
Normal weight | 245 (54.9) | ||
Overweight | 168 (37.7) | ||
Obese | 30 (6.7) | ||
Weight category at age 53, n (%) | Underweight | 232/224 (456) | 0 (0) |
Normal weight | 155 (34.0) | ||
Overweight | 220 (48.3) | ||
Obese | 81 (17.8) | ||
Weight category at age 60–64, n (%) | Underweight | 238/227 (465) | 0 (0) |
Normal weight | 143 (30.8) | ||
Overweight | 201 (43.2) | ||
Obese | 121 (26.0) | ||
Weight category at age 69, n (%) | Underweight | 236/222 (458) | 2 (0.4) |
Normal weight | 142 (31.0) | ||
Overweight | 195 (42.6) | ||
Obese | 119 (26.0) | ||
Weight category at age 71, n (%) | Underweight | 238/227 (465) | 2 (0.4) |
Normal weight | 145 (31.2) | ||
Overweight | 195 (41.9) | ||
Obese | 123 (26.5) | ||
Smoking status at age 68, n (%) | Current smoker | 238/227 (465) | 16 (3.4) |
Ex-smoker | 286 (61.5) | ||
Never smoked | 163 (35.1) | ||
Hypercholesterolaemia at age 71, n (%) | 238/227 (465) | 369 (79.4) | |
Diabetes mellitus at age 71, n (%) | 237/224 (461) | 50 (10.9) | |
SBP at age 71 in mmHg, mean (SD) | 237/227 (464) | 137.0 (16.9) | |
Adult socioeconomic position, n (%) | Non-manual (Class I-IIIN) | 238/2427 (465) | 395 (84.9) |
Manual (Class IIIM-V) | 70 (15.1) | ||
APOE-ε4 carrier (1 or 2 alleles), n (%) | 230/225 (455) | 131 (28.8) | |