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Table 1 Characteristics of included patients

From: COVID-19 in adults with dementia: clinical features and risk factors of mortality—a clinical cohort study on 125 patients

  Total (n = 125) Survivors (n = 97) Non-survivors (n = 28) p
Age 86 (82–91) 87 (82–91) 86 (82–93) 0.815
Male sex 41.6% (52) 36.1% (35) 60.7% (17) 0.029
Admission from:     0.663
 Home 59.2% (74) 57.7% (56) 64.3% (18)  
 Long-term care facility 40.8% (51) 42.3% (41) 35.7% (10)  
Medical history
 Comorbidities 91.2% (114) 91.8% (89) 89.3% (25) 0.709
 > 2 Comorbidities 67.2% (84) 67.0% (65) 67.9% (19) 0.822
 Charlson Comorbidity Index 6 (5–7) 6 (5–7) 6 (5–7) 0.292
Neurological status
Etiologies of dementia
  Unspecified cognitive impairment 60.0% (75) 59.8% (58) 60.7% (17) 1.000
  Diagnosed dementia 40.0% (50) 40.2% (39) 39.3% (11) 1.000
  Alzheimer’s disease 10.4% (13) 11.3% (11) 7.1% (2) 0.731
  Vascular dementia 7.2% (9) 6.2% (6) 10.7% (3) 0.418
  Other causes of dementia 7.2% (9) 5.2% (5) 14.3% (4) 0.113
  Parkinson disease, parkinsonian syndromes 9.6% (12) 10.3% (10) 7.1% (2) 1.000
  Psychosis 3.2% (4) 4.1% (4) 0.0% (0) 1.000
  Alcohol-related dementia 2.4% (3) 3.1% (3) 0.0% (0) 1.000
Neurological symptoms and history
  Mood disorder 31.2% (39) 33.0% (32) 25.0% (7) 0.640
  Psychotic symptoms 12.0% (15) 12.4% (12) 10.7% (3) 1.000
  History of stroke 32.0% (40) 32.0% (31) 32.1% (9) 1.000
  History of fall 38.4% (48) 36.1% (35) 46.4% (13) 0.373
  Walking before admission 70.4% (88) 70.1% (68) 71.4% (20) 1.00
  Psychotropic treatment 60.0% (75) 60.8% (59) 57.1% (16) 0.826
  Anxiolytic 30.4% (38) 32.0% (31) 25.0% (7) 0.642
  Antidepressant, mood regulator 35.2% (44) 35.1% (34) 35.7% (10) 1.000
  Neuroleptics 12.0% (15) 11.3% (11) 14.3% (4) 0.742
Non-neurological comorbidities
 Cardiovascular disease 40.8% (51) 38.1% (37) 50.0% (14) 0.383
 Arterial hypertension 80.0% (100) 79.4% (77) 82.1% (23) 1.00
 Hypercholesterolaemia 48.8% (61) 46.4% (45) 57.1% (16) 0.392
 Atrial fibrillation 24.8% (31) 24.7% (24) 25.0% (7) 1.00
 Coronaropathy 16.0% (20) 14.4% (14) 21.4% (6) 0.388
 Cardiac insufficiency 24.0% (30) 25.8% (25) 17.9% (5) 0.460
 Thrombosis 9.6% (12) 11.3% (11) 3.6% (1) 0.296
 COPD 8.8% (11) 6.2% (6) 17.9% (5) 0.068
 Respiratory insufficiency 3.2% (4) 3.1% (3) 3.6% (1) 1.000
 Diabetes 16.8% (21) 15.5% (15) 21.4% (6) 0.566
 Malnutrition 33.6% (42) 37.1% (36) 21.4% (6) 0.172
 Malignancy 9.6% (12) 11.3% (11) 3.6% (1) 0.296
 Chronic liver disease 1.6% (2) 2.1% (2) 0.0% (0) 1.000
 Chronic renal disease 16.0% (20) 11.3% (11) 32.1% (9) 0.017
  1. Data are median (IQI), % (n). P values > 0.05 (bold) indicates significant differences between survivors and non-survivors
  2. *Other causes of dementia: included mixed dementia (AD and vascular dementia, n = 7), fronto-temporal dementia (n = 1) and vascular dementia and alcohol-related dementia (respectively, n = 1)
  3. COPD chronic obstructive pulmonary disease