CSF biomarker | Time point | Interaction | 95% CI | t | P |
---|---|---|---|---|---|
Aβ42/t-tau | Time 6 | 0.1995 | − 0.1375, 0.5365 | 1.1532 | 0.2492 |
Time 12 | 0.3142 | 0.0002, 0.6282 | 1.9489 | 0.0517 | |
Time 18 | 0.7158 | 0.4114, 1.0201 | 4.5804 | 0.0000 | |
Time 24 | 0.7278 | 0.3980, 1.0576 | 4.2976 | 0.0000 | |
Time 30 | 0.6932 | 0.3525, 1.0339 | 3.9628 | 0.0001 | |
Time 36 | 0.8985 | 0.5423, 1.2548 | 4.9123 | 0.0000 | |
Aβ42 | Time 6 | 0.0011 | −0.0006, 0.0028 | 1.2622 | 0.2073 |
Time 12 | 0.0013 | − 0.0004, 0.0030 | 1.5417 | 0.1236 | |
Time 18 | 0.0028 | 0.0011, 0.0046 | 3.2476 | 0.0012 | |
Time 24 | 0.0030 | 0.0012, 0.0049 | 3.1770 | 0.0015 | |
Time 30 | 0.0030 | 0.0009, 0.0052 | 2.7235 | 0.0066 | |
Time 36 | 0.0035 | 0.0014, 0.0056 | 3.2335 | 0.0013 | |
p181-tau | Time 6 | −0.0084 | −0.0252, 0.0085 | −0.9701 | 0.3323 |
Time 12 | −0.0133 | −0.0294, 0.0029 | −1.5972 | 0.1106 | |
Time 18 | −0.0267 | −0.0438, − 0.0096 | −3.0428 | 0.0024 | |
Time 24 | −0.0225 | −0.0398, − 0.0052 | −2.5298 | 0.0116 | |
Time 30 | −0.0220 | −0.0405, − 0.0036 | −2.3239 | 0.0204 | |
Time 36 | −0.0376 | −0.0585, − 0.0168 | − 3.5146 | 0.0005 | |
t-tau | Time 6 | −0.0009 | − 0.0030, 0.0011 | − 0.8744 | 0.3821 |
Time 12 | −0.0018 | −0.0037, 0.0002 | −1.7530 | 0.0800 | |
Time 18 | −0.0042 | −0.0062, − 0.0022 | −4.1350 | 0.0000 | |
Time 24 | −0.0035 | −0.0056, − 0.0014 | −3.2733 | 0.0011 | |
Time 30 | −0.0036 | −0.0058, − 0.0014 | −3.1591 | 0.0016 | |
Time 36 | −0.0050 | −0.0075, − 0.0026 | −4.0395 | 0.0001 |