Fig. 3From: Prognostic value of amyloid/tau/neurodegeneration (ATN) classification based on diagnostic cerebrospinal fluid samples for Alzheimer’s diseaseInteraction of individual continuous CSF biomarkers on the slope of MMSE within ATN classes. The more negative the value of the slope, the steeper the cognitive decline. a The effect of CSF ratio Aβ42/t-tau. b The effect of Aβ42. c The effect of CSF t-tau. d The effect of p181-tau. The dashed line corresponds to the CSF cut-off for each particular biomarker. MMSE, Mini Mental State Examination; CSF, cerebrospinal fluid; Aβ42, amyloid-beta 1–42; t-tau, total tau; p181-tau, hyperphosphorylated tau at threonine 181Back to article page