Alzheimer's Research & Therapy

Table 3 Associations of plasma NfL and p-tau181 levels with CDRSoB and MMSE change

From: Plasma neurofilament light and phosphorylated tau 181 as biomarkers of Alzheimer’s disease pathology and clinical disease progression

	ΔCDRSoB			ΔMMSE
	Variable	Coeff.	p-value	Variable	Coeff.	p-value
CN	NfL	0.386	0.001	NfL	− 0.142	0.240
CN	p-tau181	− 0.056	0.620	p-tau181	0.030	0.801
CI	NfL	0.227	0.035	NfL	− 0.145	0.230
CI	p-tau181	0.252	0.020	p-tau181	− 0.293	0.017

Linear regression models with changes in CDRSoB (ΔCDRSoB) or MMSE (ΔMMSE) at last follow-up as dependent variables with plasma NfL or p-tau181 levels. For each variable, standardized coefficients (Coeff.) and significance are shown

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ISSN: 1758-9193

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