Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport

Table 7 Spearman’s correlation analysis between KIF5 members when normalized to GAPDH in human AD-DS frontal cortex samples

Sample type			Sample size (n)	Correlation coefficient (r)	Significance (P)
C/AD-DS and AD-DS	KIF5A	KIF5B	40	0.4850	0.0015**
C/AD-DS and AD-DS	KIF5A	KIF5C	40	0.6572	< 0.0001***
C/AD-DS and AD-DS	KIF5B	KIF5C	40	0.6225	< 0.0001***
AD-DS	KIF5A	KIF5B	21	0.6301	0.0029**
AD-DS	KIF5A	KIF5C	21	0.8150	< 0.0001***
AD-DS	KIF5B	KIF5C	21	0.6992	0.0006***
C/AD-DS	KIF5A	KIF5B	19	0.2965	0.2177
C/AD-DS	KIF5A	KIF5C	19	0.4825	0.0364*
C/AD-DS	KIF5B	KIF5C	19	0.4789	0.0380*
C/COMB	KIF5A	KIF5B	21	0.4805	0.0236*
C/COMB	KIF5A	KIF5C	21	0.5088	0.0156*
C/COMB	KIF5B	KIF5C	21	0.5178	0.0136*

ISSN: 1758-9193