Normal levels of KIF5 but reduced KLC1 levels in both Alzheimer disease and Alzheimer disease in Down syndrome: evidence suggesting defects in anterograde transport

Table 6 Spearman’s correlation analysis between KIF5 members when normalized to β-actin in human AD-DS frontal cortex samples

Sample type			Sample size (n)	Correlation coefficient (r)	Significance (P)
AD-DS	KIF5A	KIF5B	21	0.7143	0.0003***
AD-DS	KIF5A	KIF5C	21	0.6059	0.0036**
AD-DS	KIF5B	KIF5C	21	0.6057	0.0036**
C/AD-DS	KIF5A	KIF5B	19	0.3632	0.1265
C/AD-DS	KIF5A	KIF5C	19	0.6947	0.0010***
C/AD-DS	KIF5B	KIF5C	19	0.5684	0.0111*
C/COMB	KIF5A	KIF5B	21	0.5013	0.0206*
C/COMB	KIF5A	KIF5C	21	0.7688	< 0.0001***
C/COMB	KIF5B	KIF5C	21	0.6584	0.0012**

ISSN: 1758-9193