Fig. 5

Reduction of TH expression in the ventral olfactory periglomerular cells of 5xFAD mice. a–b TH (+) (green) PG cells were identified in the olfactory glomeruli of WT versus 5xFAD mice (WT, n = 4; 5xFAD, n = 3). a The local intensity of TH (+) PG cells. b Quantitative analysis of TH (+) PG cells/5 GL cells. Data are represented as means ± SEMs from three independent experiments. For statistical analysis, a two-way ANOVA was performed, followed by the Bonferroni post hoc test. Statistical significances are denoted (ns, non-significant; **P <  0.01). Wild-type (WT), five familial AD mutations (5xFAD), Alzheimer’s disease (AD)