|
Cognitive status
|
Superficial capillary plexus
|
Deep capillary plexus
|
|---|
|
Mean ± SD
|
β
|
95 CI
|
P value*
|
Mean ± SD
|
β
|
95 CI
|
P value*
|
|---|
|
Perfusion density of large vessels (%)
|
|
Control
|
6.92 ± 1.16
|
Reference
|
–
| |
–
| |
|
MCI
|
6.39 ± 1.27
|
− 0.53
|
− 1.15 to 0.09
|
0.091
|
–
|
–
|
–
|
–
|
|
AD
|
7.02 ± 1.29
|
0.10
|
− 0.61 to 0.81
|
0.787
|
–
|
–
|
–
|
–
|
|
Foveal avascular zone area (mm2)
|
|
Control
|
0.31 ± 0.12
|
Reference
|
1.11 ± 0.47
|
Reference
|
|
MCI
|
0.35 ± 0.12
|
0.041
|
− 0.02 to 0.10
|
0.190
|
1.24 ± 0.39
|
0.129
|
− 0.07 to 0.33
|
0.197
|
|
AD
|
0.34 ± 0.14
|
0.034
|
− 0.04 to 0.11
|
0.380
|
1.13 ± 0.43
|
0.016
|
− 0.23 to 0.26
|
0.898
|
- AD Alzheimer’s disease, CI confidence intervals, MCI mild cognitive impairment, SD standard deviation
- *Adjusted for age, gender, race, diabetes, blood pressure (systolic and diastolic levels), and signal strength of OCTA scans
