| Affected individuals (n = 20) | Healthy at-risk relatives (n = 11) |
---|---|---|
Sociodemographics | ||
 Age (years) | 66.0 + 12.8 | 38.4 + 11.7 |
 Gender (F) | 18 (90%) | 8 (73%) |
 Education | ||
  Middle school | 14 (70%) | 2 (18%) |
  High school | 3 (15%) | 6 (55%) |
  University | 3 (15%) | 3 (27%) |
 Married | 19 (95%) | 4 (36%) |
Geographical origin | ||
 Northern Italy | 18 (90%) | 11 (100%) |
 Centre of Italy | 1 (5%) | 0 (0%) |
 Southern Italy | 1 (5%) | 0 (0%) |
Suspected diagnosis | ||
 Inherited AD | 17 (85%) | – |
 Inherited FTD | 2 (10%) | – |
 IBMPFD | 1 (5%) | – |
Age at dementia onset (years) | 59.1 + 10.0 | – |
Cognitive severity | ||
 Clinical Dementia Rating scale score |  |  |
  0 | 1 (5%) | – |
  0.5–1 | 5 (25%) | – |
  ≥ 2 | 14 (70%) | – |
Expected time to disease onset (years)* | ||
 0–15 | – | 4 (36%) |
 16–30 | – | 6 (55%) |
 > 30 | – | 1 (9%) |