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Table 2 Demographical and clinical characteristics

From: Combination of snapshot hyperspectral retinal imaging and optical coherence tomography to identify Alzheimer’s disease patients

Parameter

Alzheimer’s disease (AD) patients (n = 17)

Controls (n = 22)

P

Time since AD diagnosis (years)

2.7 ± 2.6

NA

Age (years)

71.9 ± 6.6

68.6 ± 8.4

0.193*

Sex (male/female)

7/10

12/9

0.267

Body mass index (kg/m2)

24.9 ± 2.9

26.0 ± 4.4

0.412*

Eye (right/left)

10/7

10/12

0.408

MMSE

17.6 ± 5.5

29.3 ± 0.9

< 0.001

BCVA (logMAR)

0.14 ± 0.11

0.06 ± 0.08

0.027*

IOP (mmHg)

14 ± 3

15 ± 4

0.359*

Phakic (yes/no)

15/2

12/10

0.024

Vertical cup/disc ratio

0.52 ± 0.15

0.51 ± 0.21

0.878*

RNFLAVG (μm)

84.8 ± 7.5

92.1 ± 7.3

0.005§

RNFLSUP (μm)

104.2 ± 8.9

109.8 ± 12.4

0.019§

RNFLINF (μm)

104.3 ± 11.1

115.6 ± 11.4

0.009§

RNFLTEM (μm)

63.3 ± 8.1

70.4 ± 6.7

0.069§

RNFLNAS (μm)

66.3 ± 11.7

72.7 ± 8.6

0.012§

  1. MMSE Mini-Mental State Examination, BCVA best corrected visual acuity, RNFL retinal nerve fiber layer. Data are presented as mean ± standard deviation
  2. *Independent samples t test
  3. Mann-Whitney U test
  4. Chi-square test
  5. §Multivariate linear regression corrected for age, gender, and image quality