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Table 2 Demographical and clinical characteristics

From: Combination of snapshot hyperspectral retinal imaging and optical coherence tomography to identify Alzheimer’s disease patients

Parameter Alzheimer’s disease (AD) patients (n = 17) Controls (n = 22) P
Time since AD diagnosis (years) 2.7 ± 2.6 NA
Age (years) 71.9 ± 6.6 68.6 ± 8.4 0.193*
Sex (male/female) 7/10 12/9 0.267
Body mass index (kg/m2) 24.9 ± 2.9 26.0 ± 4.4 0.412*
Eye (right/left) 10/7 10/12 0.408
MMSE 17.6 ± 5.5 29.3 ± 0.9 < 0.001
BCVA (logMAR) 0.14 ± 0.11 0.06 ± 0.08 0.027*
IOP (mmHg) 14 ± 3 15 ± 4 0.359*
Phakic (yes/no) 15/2 12/10 0.024
Vertical cup/disc ratio 0.52 ± 0.15 0.51 ± 0.21 0.878*
RNFLAVG (μm) 84.8 ± 7.5 92.1 ± 7.3 0.005§
RNFLSUP (μm) 104.2 ± 8.9 109.8 ± 12.4 0.019§
RNFLINF (μm) 104.3 ± 11.1 115.6 ± 11.4 0.009§
RNFLTEM (μm) 63.3 ± 8.1 70.4 ± 6.7 0.069§
RNFLNAS (μm) 66.3 ± 11.7 72.7 ± 8.6 0.012§
  1. MMSE Mini-Mental State Examination, BCVA best corrected visual acuity, RNFL retinal nerve fiber layer. Data are presented as mean ± standard deviation
  2. *Independent samples t test
  3. Mann-Whitney U test
  4. Chi-square test
  5. §Multivariate linear regression corrected for age, gender, and image quality