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Fig. 6 | Alzheimer's Research & Therapy

Fig. 6

From: Behavioral, neuromorphological, and neurobiochemical effects induced by omega-3 fatty acids following basal forebrain cholinergic depletion in aged mice

Fig. 6

Morphological analyses. a–c Graphs showing the variations of volume in the whole hippocampus, CA1+CA3, and dentate gyrus (DG) in the four experimental groups. d Graph showing the large increase of BrdU+ cells in n-3 PUFA (sham and sap) groups when compared to their relative oil groups. e Graph representing the increased number of SOX2+ sub-population in the n-3 PUFA (sham and sap) groups in respect to their relative oil groups. f Graph showing the enhancement of DCX+ neuroblasts in sap n-3 PUFA group in comparison with sap oil group. g Graph indicating the increased number of GFAP+ cells in sap oil vs. sham oil mice and the decreased number of GFAP+ cells in sap n-3 PUFA vs. sap oil mice. h Representative images showing the increase of the BrdU+ cells (indicated by arrowheads) in the DG of the sham n-3 PUFA and sap n-3 PUFA groups. Scale bar 100 μm. *p < 0.05, ***p < 0.001. DG, dentate gyrus

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Alzheimer's Research & Therapy

ISSN: 1758-9193