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Table 2 MD values

From: Measuring cortical mean diffusivity to assess early microstructural cortical change in presymptomatic familial Alzheimer’s disease

  Controls Early presymptomatic Late presymptomatic Symptomatic
Entorhinal cortex MD (SD) 7.43 (0.52) 7.73 (0.46) 7.50 (0.64) 8.49 (1.03)**
Inferior parietal cortex MD (SD) 7.89 (0.24) 7.93 (0.36) 8.19 (0.26)* 9.26 (0.55)**
Precuneus MD (SD) 8.18 (0.28) 8.07 (0.33) 8.43 (0.42)* 9.50 (0.62)**
Superior frontal cortex MD (SD) 7.98 (0.28) 7.84 (0.22) 7.99 (0.37) 8.89 (0.57)**
Superior parietal cortex MD (SD) 8.34 (0.35) 8.32 (0.35) 8.52 (0.36) 9.58 (0.66)**
Supramarginal cortex MD (SD) 8.04 (0.36) 7.95 (0.36) 8.15 (0.31) 9.24 (0.62)**
  1. Observed mean (SD) MD values (mm2/s × 10−3) are shown for each cortical ROI across the four groups. For comparison of MD, linear regression was used, adjusted for age and sex
  2. MD mean diffusivity
  3. *Evidence of a difference (p < 0.05) compared with controls
  4. **Evidence of a difference (p < 0.001) compared with controls