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Table 2 MD values

From: Measuring cortical mean diffusivity to assess early microstructural cortical change in presymptomatic familial Alzheimer’s disease

 

Controls

Early presymptomatic

Late presymptomatic

Symptomatic

Entorhinal cortex MD (SD)

7.43 (0.52)

7.73 (0.46)

7.50 (0.64)

8.49 (1.03)**

Inferior parietal cortex MD (SD)

7.89 (0.24)

7.93 (0.36)

8.19 (0.26)*

9.26 (0.55)**

Precuneus MD (SD)

8.18 (0.28)

8.07 (0.33)

8.43 (0.42)*

9.50 (0.62)**

Superior frontal cortex MD (SD)

7.98 (0.28)

7.84 (0.22)

7.99 (0.37)

8.89 (0.57)**

Superior parietal cortex MD (SD)

8.34 (0.35)

8.32 (0.35)

8.52 (0.36)

9.58 (0.66)**

Supramarginal cortex MD (SD)

8.04 (0.36)

7.95 (0.36)

8.15 (0.31)

9.24 (0.62)**

  1. Observed mean (SD) MD values (mm2/s × 10−3) are shown for each cortical ROI across the four groups. For comparison of MD, linear regression was used, adjusted for age and sex
  2. MD mean diffusivity
  3. *Evidence of a difference (p < 0.05) compared with controls
  4. **Evidence of a difference (p < 0.001) compared with controls
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Alzheimer's Research & Therapy

ISSN: 1758-9193