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Table 1 Demographic and clinical characteristics of participants

From: Association of carotid and intracranial stenosis with Alzheimer’s disease biomarkers

Variables CN (N = 281) CI (N = 199) p value
Age, years 69.1 ± 8.1 72.9 ± 7.4 < 0.001*
Females 146 (52.0%) 134 (67.3%) 0.001*
Education, years 11.9 ± 4.8 9.7 ± 4.9 < 0.001*
APOE4 carriers 52 (18.5%) 83 (41.7%) < 0.001*
Global CDR (0/0.5/1) 281/0/0 0/153/46 < 0.001*
CDR-SOB 0.0 ± 0.1 2.7 ± 2.0 < 0.001*
Hypertension 133 (47.3%) 99 (49.7%) 0.602
Diabetes mellitus 46 (16.4%) 34 (17.1%) 0.836
Coronary artery disease 16 (5.7%) 10 (5.0%) 0.470
Hyperlipidemia 96 (34.2%) 71 (35.7%) 0.731
Stroke 0 (0.0%) 0 (0.0%) NA
Transient ischemic attack 2 (0.7%) 1 (0.5%) 0.774
Vascular risk factor score 17.4 ± 16.11 18.0 ± 16.8 0.679
WMH volume (cm3)a 5.7 ± 5.3 6.4 ± 5.2 0.202
  1. Data are presented as mean ± SD or n (%)
  2. CN cognitively normal, CI cognitively impaired, MCI mild cognitive impairment, AD dementia, Alzheimer’s dementia, CDR-SOB Clinical Dementia Rating sum of box, WMH white matter hyperintensities
  3. aData for 422 individuals were available (256 CN and 166 CI)
  4. *p < 0.05