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Table 1 Demographic and clinical characteristics of participants

From: Association of carotid and intracranial stenosis with Alzheimer’s disease biomarkers

Variables

CN (N = 281)

CI (N = 199)

p value

Age, years

69.1 ± 8.1

72.9 ± 7.4

< 0.001*

Females

146 (52.0%)

134 (67.3%)

0.001*

Education, years

11.9 ± 4.8

9.7 ± 4.9

< 0.001*

APOE4 carriers

52 (18.5%)

83 (41.7%)

< 0.001*

Global CDR (0/0.5/1)

281/0/0

0/153/46

< 0.001*

CDR-SOB

0.0 ± 0.1

2.7 ± 2.0

< 0.001*

Hypertension

133 (47.3%)

99 (49.7%)

0.602

Diabetes mellitus

46 (16.4%)

34 (17.1%)

0.836

Coronary artery disease

16 (5.7%)

10 (5.0%)

0.470

Hyperlipidemia

96 (34.2%)

71 (35.7%)

0.731

Stroke

0 (0.0%)

0 (0.0%)

NA

Transient ischemic attack

2 (0.7%)

1 (0.5%)

0.774

Vascular risk factor score

17.4 ± 16.11

18.0 ± 16.8

0.679

WMH volume (cm3)a

5.7 ± 5.3

6.4 ± 5.2

0.202

  1. Data are presented as mean ± SD or n (%)
  2. CN cognitively normal, CI cognitively impaired, MCI mild cognitive impairment, AD dementia, Alzheimer’s dementia, CDR-SOB Clinical Dementia Rating sum of box, WMH white matter hyperintensities
  3. aData for 422 individuals were available (256 CN and 166 CI)
  4. *p < 0.05