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Table 4 Differences in LAS-FNAME performance between symptomatic PSEN1 mutation carriers and non-carriers

From: The Latin American Spanish version of the Face-Name Associative Memory Exam is sensitive to cognitive and pathological changes in preclinical autosomal dominant Alzheimer’s disease

  Non-carriers (n = 48) Symptomatic carriers (n = 19)
LAS-FNAME M (SD) M (SD) df F p valuea d
Immediate Memory
 Face Recognition 11.71 (.79) 10.84 (1.71) 1, 111 2.53 .114 .38
 Letter Recall 4.88 (2.60) 2.84 (1.89) 1, 111 5.25 .024* .49
 Name Recognition 9.83 (1.70) 7.00 (2.21) 1, 111 18.61 .000* .86
Delayed Memory
 Face Recognition 11.81 (.53) 10.58 (1.80) 1, 111 3.68 .058 .47
 Letter Recall 6.06 (2.98) 3.11 (2.05) 1, 111 11.12 .001* .70
 Name Recognition 9.27 (2.39) 7.11 (1.91) 1, 111 6.71 .011* .52
Scale Scores
 IM Total 26.42 (4.19) 20.68 (4.40) 1, 111 12.58 .001* .75
 DM Total 27.14 (4.88) 20.79 (4.43) 1, 111 11.45 .001* .71
 LAS-FNAME Total 53.56 (8.76) 41.47 (8.32) 1, 111 12.77 .001* .76
  1. Note: Symptomatic carriers include participants with FAST scores of 2 and 3 indicating presence of subjective cognitive concerns and mild cognitive impairment, respectively
  2. Abbreviations: M mean, SD standard deviation, IM Immediate Memory, DM Delayed Memory, LAS-FNAME Total IM Total + DM Total, df degrees of freedom, F F-ratio, d Cohen’s d effect size
  3. ap value calculated for ANOVA tests for all PSEN1 mutation carriers (i.e., cognitively intact, subjective cognitive concerns, and mild cognitive impairment) versus non-carriers
  4. *p < 0.05