From: Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer’s disease
%APP unbound to the lectin | |||||
---|---|---|---|---|---|
sAPPα | sAPPβ | ||||
Sample | APP specie | Con A | PHA | Con A | PHA |
NDC | APP695 | 12.2 ± 1.7 [7.3–20.6] | 6.6 ± 0.8 [4.3–9.4] | 2.9 ± 0.8 [0.3–7.1] | 2.6 ± 0.8 [0.2–6.8] |
APP-KPI | 13.7 ± 2.1 [9.2–24.6] | 5.7 ± 0.8 [2.8–8.1] | 40.4 ± 4.6 [20.2–58.3] | 37.0 ± 3.2 [22.6–51.0] | |
AD | APP695 | 7.0 ± 1.5 [2.4–12.9] | 4.0 ± 0.6 [1.8–6.8] | 1.2 ± 0.5 [0.1–3.7] | 1.9 ± 0.3 [1.0–3.1] |
APP-KPI | 7.7 ± 1.3 [4.0–12.4] | 3.8 ± 0.6 [2.3–5.4] | 57.1 ± 8.5 [37.6–89.0] | 56.7 ± 9.7 [27.4–95.3] |