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Table 1 Effect of exercise under exposure to the 40-Hz light flickering on spatial learning and memory and long-term memory

From: Physical exercise during exposure to 40-Hz light flicker improves cognitive functions in the 3xTg mouse model of Alzheimer’s disease

  Spatial learning training (s) SM (%) LTM (s)
Group 1 day 2 days 3 days 4 days 5 days
CON 45.00 ± 3.76 24.20 ± 4.54 29.00 ± 3.71 17.07 ± 4.06 13.73 ± 2.54 33.57 ± 1.97 203.60 ± 23.73
AD 60.00 ± 0.0* 57.67 ± 1.17* 52.75 ± 3.71* 43.25 ± 3.88* 34.92 ± 5.78* 16.93 ± 2.31* 54.40 ± 16.90*
AD+40 51.93 ± 4.33 42.67 ± 4.40* 29.53 ± 5.34# 17.40 ± 3.37# 14.53 ± 3.63# 29.10 ± 1.42*# 161.20 ± 10.95*#
AD+EX 58.00 ± 2.05 54.05 ± 2.05* 31.08 ± 4.58# 19.08 ± 3.06# 15.50 ± 1.32# 31.08 ± 3.66*# 168.40 ± 24.86*#
AD+40+EX 52.56 ± 3.22 39.94 ± 4.87* 22.11 ± 3.48# 13.17 ± 3.38# 10.83 ± 2.22# 43.01 ± 2.05*#+ 250.83 ± 28.29*#+
  1. *P < .05 compared to the CON group, #P < .05 compared to the AD group, +P < .05 compared to the AD+40 and AD+EX. SM spatial memory, LTM long-term memory
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Alzheimer's Research & Therapy

ISSN: 1758-9193