Fig. 3
From: APOE ε4 genotype-dependent cerebrospinal fluid proteomic signatures in Alzheimer’s disease
![Fig. 3](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13195-020-00628-z/MediaObjects/13195_2020_628_Fig3_HTML.png)
Effect size plots for 114 proteins measured in both ADNI and EMIF-AD MBD studies. a Effects for protein differences of individuals with abnormal amyloid carrying and ≥ 1 APOE ε4 allele against controls (i.e., APOE ε4 non-carriers with normal amyloid and MMSE > 27) according to the severity of their cognitive impairment (MMSE > 27, 27–24, or < 24), and at the far left for APOE ε4 carriers with normal amyloid and MMSE > 27. In blue, effect sizes and 95%CI for ADNI; in orange, for EMIF-AD MBD. b Effects for protein differences of individuals with abnormal amyloid carrying without an APOE ε4 allele against controls (i.e., APOE ε4 non-carriers with normal amyloid and MMSE > 27) according to the severity of their cognitive impairment (MMSE > 27, 27–24, or < 24). In blue, effect sizes and 95%CI for ADNI; in orange, for EMIF-AD MBD