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Table 1 Demographic and neuropsychological features in single EOAD patient

From: The combined effects of microglia activation and brain glucose hypometabolism in early-onset Alzheimer’s disease

  EOAD1 EOAD2 EOAD3 EOAD4 EOAD5 EOAD6 EOAD7 EOAD8 EOAD9 EOAD10 EOAD11 EOAD12
Age, years 68 55 56 64 58 59 64 58 54 56 63 66
Education, years 5 13 13 8 13 8 8 8 8 13 8 5
Sex F M M F F M F F M F F M
Disease duration, years 5 1 1 3 2 1 1 5 1 2 3 2
Diagnosis tAD tAD tAD tAD fAD fAD fAD fAD fAD fAD PCA PCA
MMSE 20 21 17 22 18 10 12 18 17 22 21 21
Token test 31 31 23.5 29 23 11.5 19.25 22.25 33 31 27.5 30.5
PVF 27 10 7 29 16 6 3 13 22 31 56 44
SVF 30.1 8 18.5 42.8 12 16 8 13 45.5 44 29.2 59.2
Span forward 6.39 4.84 2.83 5.13 5.75 6.13 2.92 5.04 2.92 5.83 4.13 6.02
Span backward 4.53 < 3 < 3 3.19 < 3 < 3 < 3 3.1 < 3 3.79 4.19 < 3
RAVLT IR 22.1 14.8 13.8 24.3 10 UT UT 0 36 41 21.5 32.3
RAVLT DR 0 0 0 0 1.5 UT UT 0 4.2 4 3 3.6
ROF recall 8 UT 0 8.5 5.25 UT 0 5 5.75 11.75 0 7.5
ROF copy 9 UT 0 23 13.25 3 7.25 28.5 29.25 14.75 0 24.25
CDT 1 10 2 5 5 0 0 0 10 7 0 10
Attentive Matrix 36 UT 12.5 31.25 23 UT 17.5 23 22 49 34.25 23
Stroop time 33.5 28 44.25 36.75 29.25 UT UT UT 46.8 46.17 44.25 27
Stroop errors 9.5 3.5 13 11.25 26.5 UT UT UT 5 0 5.25 2.5
Raven PM 19.5 UT 14 19 UT UT UT 21.5 26.5 22 12 31.5
  1. EOAD early-onset Alzheimer disease, AD Alzheimer disease, tAD typical AD, fAD frontal Alzheimer disease, PCA posterior cortical atrophy, MMSE mini mental state examination, PVF phonological verbal fluency, SVP semantic verbal fluency, RAVLT Rey auditory verbal learning task, IR immediate recall, DR delayed recall, ROF Rey-Osterrieth figure, CDT clock drawing test, Raven PM Raven Progressive Matrices, UT untestable
  2. For neuropsychological assessment, pathological scores are reported in bold
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Alzheimer's Research & Therapy

ISSN: 1758-9193