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Table 4 Significant associations in the CMC dorsolateral prefrontal cortex and corresponding GTEx association statistics

From: An analysis of genetically regulated gene expression across multiple tissues implicates novel gene candidates in Alzheimer’s disease

CMC (DLFPC)

GTEx (48 tissues)

Gene

Z

P

Tissue

Z

Z SD

P

TOMM40

− 21.40

1.37 × 10−101

Oesophagus mucosa

0.57

3.44

1.10 × 10−7

ZNF222

13.93

4.11 × 10−44

IRF2BP1

12.28

1.21 × 10−34

Heart atrial appendage

− 0.94

0.73

4.34 × 10−1

EML2

7.98

1.50 × 10−15

Cerebellar hemisphere

− 0.22

2.72

4.01 × 10−10

CR1

7.91

2.63 × 10−15

Oesophagus muscularis

4.30

3.45

1.69 × 10−11

CLPTM1

− 6.30

2.94 × 10−10

Skin, sun-exposed leg

− 2.98

4.89

3.35 × 10−23

TRAPC6A

− 6.29

3.22 × 10−10

Thyroid

− 1.02

2.84

2.26 × 10−13

ZNF45

− 6.12

9.18 × 10−10

Stomach

0.19

2.72

2.47 × 10−23

DMWD

5.91

3.48 × 10−9

Adipose visceral omentum

3.45

1.45

3.08 × 10−8

ZNF223

5.90

3.69 × 10−9

Brain cerebellum

1.03

1.17

5.88 × 10−4

PVR

− 4.82

1.41 × 10−6

Spleen

− 4.64

2.05

9.68 × 10−27

AP2A2

− 4.65

3.30 × 10−6

Heart atrial appendage

− 0.30

1.93

2.48 × 10−2

  1. DLPFC dorsolateral prefrontal cortex