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Table 1 Demographic characteristics of the study cohort

From: Association between retinal thickness and β-amyloid brain accumulation in individuals with subjective cognitive decline: Fundació ACE Healthy Brain Initiative

 PET status at v0PET status at v2Clinical status at v2
Aβ−Aβ+pAβ−Aβ+pSCDMCIp
n11415N/A10722N/A11415N/A
Age64.22 ± 7.4168.49 ± 4.760.03*65.70 ± 7.2970.82 ± 5.480.002*65.76 ± 6.7772.73. ± 8.12< 0.001*
Females (%)71 (62.3%)10 (66.7%)0.7468 (63.55%)13 (59.1%)0.6972 (63.16%)9 (60%)0.85
Years of education12.58 ± 3.9411.80 ± 3.990.4812.56 ± 3.9112.14 ± 4.160.6512.80 ± 3.8610.07 ± 3.830.01*
MMSE29.32 ± 0.9029.53 ± 0.740.3929.22 ± 1.0329.11 ± 1.320.7229.33 ± 0.8828.25 ± 1.820.06
APOE ε4+ (%)21 (18.4%)11 (73.7%)< 0.001*21 (19.6%)11 (50%)0.003*24 (21.05%)8 (53.3%)0.007*
  1. A T test was used to analyse differences on age, years of education and MMSE between groups. A Chi-square test was employed to analyse differences on the distribution of females and APOE genotype between groups
  2. *Statistical significance was set-up at p < 0.05
  3. Abbreviations: amyloid-β, APOE apolipoprotein E, MMSE Mini-Mental State Examination, PET positron emission tomography, MCI mild cognitive impairment, SCD subjective cognitive decline, v0 baseline visit, v2 2-year follow-up visit