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Table 3 APOE ε4 allele frequency and plasma biomarkers between amyloid positive and negative

From: Plasma amyloid assay as a pre-screening tool for amyloid positron emission tomography imaging in early stage Alzheimer’s disease

Amyloid PET

Positive

Negative

APOE ε4 allele frequency

31.8%

3.33%

Plasma Aβ1–40 (pg/ml)

50.9 ± 7.7

49.1 ± 7.3

Plasma Aβ1–42 (pg/ml)

16.3 ± 2.3

17.6 ± 3.3*

Plasma Tau (pg/ml)

18.4 ± 8.5

22.5 ± 10.4

Plasma Aβ1–42/Aβ1–40

0.334 ± 0.109

0.374 ± 0.117

Plasma Aβ1–42xtau

316.6 ± 207.6

427.8 ± 272.1

  1. Abbreviations: Amyloid β, PET positron emission tomography
  2. *P value < 0.05