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Table 3 APOE ε4 allele frequency and plasma biomarkers between amyloid positive and negative

From: Plasma amyloid assay as a pre-screening tool for amyloid positron emission tomography imaging in early stage Alzheimer’s disease

Amyloid PET Positive Negative
APOE ε4 allele frequency 31.8% 3.33%
Plasma Aβ1–40 (pg/ml) 50.9 ± 7.7 49.1 ± 7.3
Plasma Aβ1–42 (pg/ml) 16.3 ± 2.3 17.6 ± 3.3*
Plasma Tau (pg/ml) 18.4 ± 8.5 22.5 ± 10.4
Plasma Aβ1–42/Aβ1–40 0.334 ± 0.109 0.374 ± 0.117
Plasma Aβ1–42xtau 316.6 ± 207.6 427.8 ± 272.1
  1. Abbreviations: Amyloid β, PET positron emission tomography
  2. *P value < 0.05