Table 2 Numbers, amyloid PET positive percentage, and plasma biomarkers in APOE ε4 carriers and non-carriers
APOE genotype | ε4 carriers | ε4 non-carriers | |
|---|---|---|---|
ε4 carriers (ε2ε4, ε3ε4, ε4ε4) | All ε4 non-carriers (ε2ε2, ε2ε3, ε3ε3) | ε4 carriers (ε2ε2, ε2ε3) | |
Amyloid PET+% | 85.7% | 26.3% | 0 |
Plasma Aβ1–40 (pg/ml) | 47.1 ± 7.2 | 50.9 ± 7.4 | 50.0 ± 8.5 |
Plasma Aβ1–42 (pg/ml) | 17.9 ± 2.9 | 16.7 ± 2.9 | 16.5 ± 2.7 |
Plasma tau (pg/ml) | 24.7 ± 9.9 | 19.3 ± 9.5* | 18.8 ± 8.2 |
Plasma Aβ1–42/Aβ1–40 | 0.396 ± 0.117 | 0.343 ± 0.111 | 0.349 ± 0.126 |
Plasma Aβ1–42xtau (pg2/ml2) | 468.2 ± 262.2 | 348.6 ± 242.1 | 331.0 ± 208.6 |