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Table 2 Numbers, amyloid PET positive percentage, and plasma biomarkers in APOE ε4 carriers and non-carriers

From: Plasma amyloid assay as a pre-screening tool for amyloid positron emission tomography imaging in early stage Alzheimer’s disease

APOE genotypeε4 carriersε4 non-carriers
ε4 carriers (ε2ε4, ε3ε4, ε4ε4)All ε4 non-carriers (ε2ε2, ε2ε3, ε3ε3)ε4 carriers (ε2ε2, ε2ε3)
Amyloid PET+%85.7%26.3%0
Plasma Aβ1–40 (pg/ml)47.1 ± 7.250.9 ± 7.450.0 ± 8.5
Plasma Aβ1–42 (pg/ml)17.9 ± 2.916.7 ± 2.916.5 ± 2.7
Plasma tau (pg/ml)24.7 ± 9.919.3 ± 9.5*18.8 ± 8.2
Plasma Aβ1–42/Aβ1–400.396 ± 0.1170.343 ± 0.1110.349 ± 0.126
Plasma Aβ1–42xtau (pg2/ml2)468.2 ± 262.2348.6 ± 242.1331.0 ± 208.6
  1. Abbreviations: Amyloid β, PET positron emission tomography
  2. *P value < 0.05: ε4 carriers vs ε4 non-carriers