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Table 4 CSF protein concentrations of each synaptic measure for those with likely tau and TDP-43 pathology

From: CSF synaptic protein concentrations are raised in those with atypical Alzheimer’s disease but not frontotemporal dementia

Synaptic measure

Tau (mean (SD))

TDP-43 (mean (SD))

Control (mean (SD))

Ng22 (pg/ml)

169.0 (151.3)

103.1 (95.3)

137.6 (95.9)

Ng36 (pg/ml)

179.8 (47.2)

151.1 (75.9)

130.0 (80.9)

SNAP-25tot (pM)

56.2 (13.0)

50.6 (13.6)

53.5 (11.7)

SNAP-25aa40 (pM)

9.2 (2.0)

7.9 (2.1)

7.9 (2.3)

Synaptotagmin-1 (pM)

214.4 (65.3)

220.7 (85.0)

238.3 (71.4)