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Table 1 Baseline characteristics of the cohort

From: CSF synaptic protein concentrations are raised in those with atypical Alzheimer’s disease but not frontotemporal dementia

Participant stratificationNumberAge at CSF (mean (SD))Gender (M:F)CSF total-tau (pg/ml, mean (SD))CSF Aβ42 (pg/ml, mean (SD))Total-tau to Aβ42 ratioDisease duration (mean (SD))MMSE (mean (SD))
Control1964.2 (6.9)10:9327.9 (93.2)1012.7 (237.3)0.3 (0.1)N/AN/A
AD biomarker group1866.4 (5.9)11:7984.4 (543.6)471.1 (179.0)2.5 (2.0)3.5 (2.0)21.1 (5.2)
FTD biomarker group4864.0 (6.8)34:14376.1 (173.3)851.2 (246.1)0.5 (0.2)5.7 (4.1)23.9 (7.0)
Probable TDP-43 pathology1862.6 (5.6)13:5456.0 (226.0)863.4 (222.5)0.5 (0.3)6.6 (4.9)23.3 (6.7)
Probable tau pathology764.7 (8.9)5:2444.4 (146.4)894.3 (214.1)0.5 (0.2)5.5 (3.1)21.1 (10.4)
  1. MMSE Mini-Mental State Examination