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Fig. 3 | Alzheimer's Research & Therapy

Fig. 3

From: HHV-6A infection induces amyloid-beta expression and activation of microglial cells

Fig. 3

a mRNA apoE, IL-1beta, and TREM2 expression was evaluated in microglial cells at 1, 3, 7, and 14 d.p.i. b HHV-6A-infected microglial cells (m.o.i. 100:1; 14 d.p.i.) were stained with anti-Iba-1 FITC and TREM2 PE moAbs. Images were taken in bright field (left panel) or fluorescence (right panels) (Nikon Eclipse TE2000S) equipped with a digital camera. Original magnification × 20. c IL-1α, IL-1β, IL-6, IL-10, and tumor necrosis factor-α expression in uninfected (white histogram) and in HHV-6-infected microglial cells (gray histogram). *p value < 0.0001, obtained by Student’s t test. Each experiment was performed in triplicate

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